Semi Prep HPLC Column, NP Diol, 10um, 100A. 10mm ID x 100mm Length. Cogent Brand. 1 EA.

Additional Information:

Cogent NP Diol™ Semi-Prep HPLC Columns are designed for purification of polar and hydrophilic compounds using Normal Phase and HILIC chromatographic modes. Manufactured using ultra-high purity silica bonded with a short hydrocarbon ligand containing a terminal diol functional group, this stationary phase provides reproducible retention characteristics and selectivity for compounds that may be difficult to retain or purify using traditional reversed-phase methods. NP Diol™ is often selected as an alternative to unmodified silica columns when improved stability and polar selectivity are desired.

82060-SP100 is packed with 10 µm NP Diol™ particles in a 10 mm ID x 100 mm semi-preparative format with a 100Å pore size. The 10 µm particle size is well suited for semi-preparative chromatography, providing lower operating backpressure while allowing higher flow rates and increased sample loading compared to analytical columns. The 10 mm internal diameter is ideal for method scale-up, compound purification, and fraction collection applications.

The NP Diol™ stationary phase is non-end-capped and is ideal for purification of hydrophilic and polar compounds using either Normal Phase or HILIC conditions. The semi-preparative column format provides a practical balance between purification capacity and solvent consumption, making it suitable for laboratory-scale purification and method development workflows. NP Diol™ columns are frequently selected for purification of compounds that require an alternative to unmodified silica stationary phases.

Key Benefits

  • NP Diol™ stationary phase

  • Ultra-high purity silica support

  • Terminal diol functional group

  • Non-end-capped chemistry

  • 100Å pore size

  • 10 µm semi-preparative particle size

  • Suitable for Normal Phase chromatography

  • Suitable for HILIC applications

  • Increased loading capacity versus analytical columns

  • Ideal for semi-preparative purification and method scale-up

Typical Applications

  • Semi-preparative HPLC

  • Compound purification

  • HILIC purification

  • Normal Phase purification

  • Polar compound isolation

  • Hydrophilic compound purification

  • Natural product purification

  • Pharmaceutical research

  • Method scale-up

  • Fraction collection applications

Specifications

  • Product Type: Semi-Prep HPLC Column

  • Stationary Phase: NP Diol™

  • Chromatography Mode: Normal Phase / HILIC

  • Particle Size: 10 µm

  • Pore Size: 100Å

  • Column Dimensions: 10 mm ID x 100 mm

  • Recommended Flow Rate: 3–8 mL/min

  • Column Hardware: Stainless Steel

  • Brand: Cogent

Special Order Item Information

Important Notes

  • Suitable for Normal Phase chromatography

  • Suitable for HILIC applications

  • Designed for purification of hydrophilic and polar compounds

  • Alternative to unmodified silica columns

  • Higher loading capacity than analytical columns

  • 10 µm particles provide lower backpressure at semi-preparative flow rates

  • 10 mm ID format requires a semi-preparative capable HPLC system

  • Excellent for method scale-up from analytical separations

  • Intended for compound isolation and purification workflows

  • This is a Special Order Item


© Copyright 2026. MICROSOLV. All Rights Reserved. Website & Hosting by BlueTone Media