Process HPLC Column, NP Diol, 10um, 100A. 50mm ID x 50mm Length. Cogent Brand. 1 EA.

Additional Information:

Cogent NP Diol™ Process HPLC Columns are designed for high-capacity purification of polar and hydrophilic compounds using Normal Phase and HILIC chromatographic modes. Manufactured using ultra-high purity silica bonded with a short hydrocarbon ligand containing a terminal diol functional group, this stationary phase provides reproducible retention characteristics and selectivity for compounds that may be difficult to purify using traditional reversed-phase methods. NP Diol™ is often selected as an alternative to unmodified silica columns when improved stability and polar selectivity are desired.

82060-P50-50 is packed with 10 µm NP Diol™ particles in a 50 mm ID x 50 mm process-scale format with a 100Å pore size. The 10 µm particle size is well suited for high-throughput purification, providing lower operating backpressure while allowing high mobile phase flow rates and substantial sample loading capacity. The large 50 mm internal diameter provides excellent loading capacity, while the shorter 50 mm column length is ideal for rapid purification, process development, and high-throughput production workflows.

The NP Diol™ stationary phase is non-end-capped and is ideal for purification of hydrophilic and polar compounds using either Normal Phase or HILIC conditions. The large-diameter process column format supports efficient scale-up from preparative methods while providing excellent productivity for routine purification, fraction collection, and manufacturing operations. This column is frequently selected when fast separations and high sample throughput are the primary objectives.

Key Benefits

  • NP Diol™ stationary phase

  • Ultra-high purity silica support

  • Terminal diol functional group

  • Non-end-capped chemistry

  • 100Å pore size

  • 10 µm process-scale particle size

  • Suitable for Normal Phase chromatography

  • Suitable for HILIC applications

  • Very high sample loading capacity

  • Ideal for rapid process-scale purification

Typical Applications

  • Process HPLC

  • Production-scale purification

  • HILIC purification

  • Normal Phase purification

  • Polar compound isolation

  • Hydrophilic compound purification

  • Natural product purification

  • Pharmaceutical manufacturing

  • Process development

  • Fraction collection applications

Specifications

  • Product Type: Process HPLC Column

  • Stationary Phase: NP Diol™

  • Chromatography Mode: Normal Phase / HILIC

  • Particle Size: 10 µm

  • Pore Size: 100Å

  • Column Dimensions: 50 mm ID x 50 mm

  • Recommended Flow Rate: 80–150 mL/min

  • Column Hardware: Stainless Steel

  • Brand: Cogent

Special Order Item Information

Important Notes

  • Suitable for Normal Phase chromatography

  • Suitable for HILIC applications

  • Designed for purification of hydrophilic and polar compounds

  • Alternative to unmodified silica columns

  • Very high loading capacity for process-scale work

  • 10 µm particles provide lower backpressure at elevated flow rates

  • 50 mm ID format requires a specialized process or large-scale preparative HPLC system

  • Short 50 mm length enables rapid purification and process development

  • Intended for compound isolation and purification workflows

  • This is a Special Order Item


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