Process HPLC Column, NP Diol, Wide Pore, 10um, 300A. 50mm ID x 250mm Length. Cogent Brand. 1 EA.
Additional Information:
Cogent NP Diol™ Wide Pore Process HPLC Columns are designed for high-capacity purification of larger polar and hydrophilic compounds using Normal Phase and HILIC chromatographic modes. Manufactured using ultra-high purity silica bonded with a short hydrocarbon ligand containing a terminal diol functional group, this stationary phase provides reproducible retention characteristics and selectivity for challenging compounds that require greater pore accessibility than conventional materials. NP Diol™ Wide Pore is often selected as an alternative to unmodified silica columns when purifying larger molecules.
82060-P50-2503M is packed with 10 µm NP Diol™ Wide Pore particles in a 50 mm ID x 250 mm process-scale format with a 300Å pore size. The 10 µm particle size is optimized for high-throughput purification, providing lower operating backpressure while allowing high mobile phase flow rates and substantial sample loading capacity. The combination of a 300Å pore structure, 50 mm internal diameter, and 250 mm length provides maximum loading capacity, increased peak capacity, and enhanced chromatographic resolution for demanding large-molecule purification applications.
The NP Diol™ Wide Pore stationary phase is non-end-capped and is ideal for purification of larger hydrophilic and polar compounds using either Normal Phase or HILIC conditions. The 300Å pore size improves analyte accessibility for larger molecules, while the 50 mm ID format supports efficient scale-up, fraction collection, and production-scale purification workflows. This column is frequently selected when maximum loading capacity, high resolution, and purification of large molecules are required.
Key Benefits
NP Diol™ Wide Pore stationary phase
Ultra-high purity silica support
Terminal diol functional group
Non-end-capped chemistry
300Å wide pore structure
10 µm process-scale particle size
Suitable for Normal Phase chromatography
Suitable for HILIC applications
Very high sample loading capacity
Optimized for large molecule purification
Typical Applications
Process HPLC
Production-scale purification
Large molecule purification
HILIC purification
Normal Phase purification
Polar compound isolation
Hydrophilic compound purification
Oligosaccharide purification
Process scale-up
Fraction collection applications
Specifications
Product Type: Process HPLC Column
Stationary Phase: NP Diol™ Wide Pore
Chromatography Mode: Normal Phase / HILIC
Particle Size: 10 µm
Pore Size: 300Å
Column Dimensions: 50 mm ID x 250 mm
Recommended Flow Rate: 80–150 mL/min
Column Hardware: Stainless Steel
Brand: Cogent
Special Order Item Information
Please review the Special Order Item Information for complete details.
For pricing confirmation, availability, lead times, or application assistance, please contact MICROSOLV Customer Service.
Important Notes
Suitable for Normal Phase chromatography
Suitable for HILIC applications
Designed for purification of larger hydrophilic and polar compounds
Wide pore structure improves accessibility for larger analytes
Alternative to unmodified silica columns
Very high loading capacity for process-scale work
10 µm particles provide lower backpressure at elevated flow rates
50 mm ID format requires a specialized process or large-scale preparative HPLC system
250 mm length provides maximum retention, resolution, and loading capacity
Intended for compound isolation and purification workflows
This is a Special Order Item