Process HPLC Column, NP Diol, 10um, 100A. 50mm ID x 100mm Length. Cogent Brand. 1 EA.

Additional Information:

Cogent NP Diol™ Process HPLC Columns are designed for high-capacity purification of polar and hydrophilic compounds using Normal Phase and HILIC chromatographic modes. Manufactured using ultra-high purity silica bonded with a short hydrocarbon ligand containing a terminal diol functional group, this stationary phase provides reproducible retention characteristics and selectivity for compounds that may be difficult to purify using traditional reversed-phase methods. NP Diol™ is often selected as an alternative to unmodified silica columns when improved stability and polar selectivity are desired.

82060-P50-100 is packed with 10 µm NP Diol™ particles in a 50 mm ID x 100 mm process-scale format with a 100Å pore size. The 10 µm particle size is well suited for high-throughput purification, providing lower operating backpressure while allowing high mobile phase flow rates and substantial sample loading capacity. The 50 mm internal diameter provides significant loading capacity for scale-up applications, making this column ideal for process chromatography, production-scale purification, and large-batch separations.

The NP Diol™ stationary phase is non-end-capped and is ideal for purification of hydrophilic and polar compounds using either Normal Phase or HILIC conditions. The large-diameter process column format supports efficient scale-up from preparative methods while providing excellent productivity for routine purification, fraction collection, and manufacturing workflows.

Key Benefits

  • NP Diol™ stationary phase

  • Ultra-high purity silica support

  • Terminal diol functional group

  • Non-end-capped chemistry

  • 100Å pore size

  • 10 µm process-scale particle size

  • Suitable for Normal Phase chromatography

  • Suitable for HILIC applications

  • Very high sample loading capacity

  • Ideal for process-scale purification

Typical Applications

  • Process HPLC

  • Production-scale purification

  • HILIC purification

  • Normal Phase purification

  • Polar compound isolation

  • Hydrophilic compound purification

  • Natural product purification

  • Pharmaceutical manufacturing

  • Process scale-up

  • Fraction collection applications

Specifications

  • Product Type: Process HPLC Column

  • Stationary Phase: NP Diol™

  • Chromatography Mode: Normal Phase / HILIC

  • Particle Size: 10 µm

  • Pore Size: 100Å

  • Column Dimensions: 50 mm ID x 100 mm

  • Recommended Flow Rate: 80–150 mL/min

  • Column Hardware: Stainless Steel

  • Brand: Cogent

Special Order Item Information

Important Notes

  • Suitable for Normal Phase chromatography

  • Suitable for HILIC applications

  • Designed for purification of hydrophilic and polar compounds

  • Alternative to unmodified silica columns

  • Very high loading capacity for process-scale work

  • 10 µm particles provide lower backpressure at elevated flow rates

  • 50 mm ID format requires a specialized process or large-scale preparative HPLC system

  • Well suited for scale-up, production, and high-throughput purification

  • Intended for compound isolation and purification workflows

  • This is a Special Order Item


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