Prep HPLC Column, NP Diol, Wide Pore, 10um, 300A. 21.2mm ID x 250mm Length. Cogent Brand. 1 EA.
Additional Information:
Cogent NP Diol™ Wide Pore Preparative HPLC Columns are designed for high-capacity purification of larger polar and hydrophilic compounds using Normal Phase and HILIC chromatographic modes. Manufactured using ultra-high purity silica bonded with a short hydrocarbon ligand containing a terminal diol functional group, this stationary phase provides reproducible retention characteristics and selectivity for challenging compounds that require greater pore accessibility than conventional materials. NP Diol™ Wide Pore is often selected as an alternative to unmodified silica columns when purifying larger molecules.
82060-P21-2503M is packed with 10 µm NP Diol™ Wide Pore particles in a 21.2 mm ID x 250 mm preparative format with a 300Å pore size. The 10 µm particle size is optimized for preparative chromatography, providing lower operating backpressure while allowing high flow rates and substantial sample loading capacity. The combination of a 300Å pore structure and large preparative column dimensions makes this column especially suitable for purification of larger polar molecules.
The NP Diol™ Wide Pore stationary phase is non-end-capped and is ideal for purification of larger hydrophilic and polar compounds using either Normal Phase or HILIC conditions. The 300Å pore size improves analyte accessibility for larger molecules, while the 21.2 mm ID format supports efficient scale-up, fraction collection, and preparative purification workflows. This column is frequently used when high loading capacity and purification of larger compounds are required.
Key Benefits
NP Diol™ Wide Pore stationary phase
Ultra-high purity silica support
Terminal diol functional group
Non-end-capped chemistry
300Å wide pore structure
10 µm preparative particle size
Suitable for Normal Phase chromatography
Suitable for HILIC applications
High sample loading capacity
Optimized for larger molecule purification
Typical Applications
Preparative HPLC
Large molecule purification
HILIC purification
Normal Phase purification
Polar compound isolation
Hydrophilic compound purification
Oligosaccharide purification
Natural product purification
Method scale-up
Fraction collection applications
Specifications
Product Type: Preparative HPLC Column
Stationary Phase: NP Diol™ Wide Pore
Chromatography Mode: Normal Phase / HILIC
Particle Size: 10 µm
Pore Size: 300Å
Column Dimensions: 21.2 mm ID x 250 mm
Recommended Flow Rate: 15–30 mL/min
Column Hardware: Stainless Steel
Brand: Cogent
Special Order Item Information
Please review the Special Order Item Information for complete details.
For pricing confirmation, availability, lead times, or application assistance, please contact MICROSOLV Customer Service.
Important Notes
Suitable for Normal Phase chromatography
Suitable for HILIC applications
Designed for purification of larger hydrophilic and polar compounds
Wide pore structure improves accessibility for larger analytes
Alternative to unmodified silica columns
High loading capacity for preparative work
10 µm particles provide lower backpressure at preparative flow rates
21.2 mm ID format requires a specialized preparative HPLC system
Intended for compound isolation and purification workflows
This is a Special Order Item