Catalog Number - 68540-P50-1003M

Cogent NP Amino™ Wide Pore Process HPLC Columns are designed for large-scale purification of larger polar compounds using Normal Phase and HILIC chromatographic modes. Manufactured using the highest purity silica available bonded with a three-carbon propyl ligand containing a terminal amino functional group, this stationary phase provides unique selectivity for negatively charged and highly polar analytes. NP Amino™ Wide Pore is particularly effective for purification of complex carbohydrates, larger sugars, and compounds containing carboxylic acid functionalities.

68540-P50-1003M is packed with 5 µm NP Amino™ Wide Pore particles in a 50 mm ID x 100 mm process-scale format with a 300Å pore size. The 5 µm particle size provides excellent chromatographic efficiency while maintaining the very high loading capacity required for process-scale purification. The 300Å pore structure enhances analyte accessibility for larger molecules, while the 50 mm internal diameter supports substantial sample throughput for process development, pilot-scale purification, and manufacturing applications.

The NP Amino™ Wide Pore stationary phase is not end capped and is optimized for purification of larger polar compounds using either Normal Phase or HILIC conditions. The wide pore structure improves retention and mass transfer for complex sugars and larger molecules containing carboxylic acid groups. These columns are packed and shipped in Normal Phase solvents and are frequently selected when high loading capacity and improved accessibility for larger analytes are required.

Key Benefits

• NP Amino™ Wide Pore stationary phase

• Propyl amino bonded silica

• Not end capped

• 300Å wide pore structure

• 5 µm process-scale particle size

• Suitable for Normal Phase chromatography

• Suitable for HILIC applications

• Very high sample loading capacity

• Enhanced accessibility for larger molecules

• Ideal for process-scale purification

Typical Applications

• Process HPLC

• Complex sugar purification

• Carbohydrate isolation

• Organic acid purification

• HILIC purification

• Normal Phase purification

• Large molecule purification

• Process development

• Pilot-scale purification

• Manufacturing support purification

Specifications

• Product Type: Process HPLC Column

• Stationary Phase: NP Amino™ Wide Pore

• Chromatography Mode: Normal Phase / HILIC

• Particle Size: 5 µm

• Pore Size: 300Å

• Column Dimensions: 50 mm ID x 100 mm

• Recommended Flow Rate: 80–150 mL/min

• Column Hardware: Stainless Steel

• Brand: Cogent

Special Order Item Information

• Please review the Special Order Item Information for complete details.

• For pricing confirmation, availability, lead times, or application assistance, please contact MICROSOLV Customer Service.

Important Notes

• Suitable for Normal Phase chromatography

• Suitable for HILIC applications

• Designed for larger sugars and polar compounds

• Ideal for compounds containing carboxylic acid groups

• Propyl amino bonded stationary phase

• Wide pore structure improves accessibility for larger analytes

• Very high loading capacity for process-scale work

• 5 µm particles provide enhanced chromatographic efficiency

• 50 mm ID format requires a specialized process HPLC system

• Optimized for scale-up, pilot-scale, and production purification

• Shipped in Normal Phase solvents

• Intended for large-scale compound isolation and purification workflows

• This is a Special Order Item

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