HPLC Column, RP C8 Octyl, 3um, 4.0mm ID x 100mm Length, 100A. Special Order Item.
Additional Information:
Cogent RP C8 Octyl™ is a versatile reversed-phase HPLC stationary phase designed for the separation of hydrophobic and neutral compounds. Manufactured using a traditional octyl (C8) bonded phase on ultra-high purity silica and fully double end capped, it provides strong hydrophobic interactions while often offering reduced retention compared to C18 phases. As a USP L7 equivalent phase, it is widely used for method replacement, method development, and routine analytical separations where balanced retention and selectivity are desired.
68308-10P-4 is an HPLC column packed with 3 µm RP C8 Octyl™ particles featuring a 100 Å pore size in a 4.0 mm ID x 100 mm format. The 100 mm length provides greater chromatographic resolution than shorter 50 mm columns while maintaining practical run times for routine analyses. The 3 µm particles deliver improved efficiency and sharper peaks compared to traditional 5 µm packings. Typical operating flow rates are approximately 0.8–1.5 mL/min depending on mobile phase composition, temperature, and system configuration.
This column is particularly useful for hydrophobic and neutral compounds analyzed by reversed-phase HPLC and is especially well suited for long-chain fatty acid analysis. The C8 chemistry provides balanced retention and selectivity while often reducing excessive retention compared to more hydrophobic stationary phases. This format is an excellent choice when additional resolution is required without substantially increasing analysis time.
Key Benefits
RP C8 Octyl™ stationary phase
USP L7 equivalent chemistry
Fully double end capped
Traditional octyl (C8) bonded phase
Ultra-high purity silica support
3 µm particle size
Greater efficiency than 5 µm columns
Improved chromatographic resolution
Balanced hydrophobic retention
Excellent for long-chain fatty acid analysis
Typical Applications
USP L7 methods
Reversed-phase HPLC
Long-chain fatty acid analysis
Hydrophobic compound analysis
Neutral compound analysis
Pharmaceutical analysis
Method development
Quality control testing
Routine analytical methods
Preparative method scouting
Specifications
Product Type: HPLC Column
Stationary Phase: RP C8 Octyl™
USP Classification: L7
Chromatography Mode: Reversed Phase
Bonded Phase: Octyl (C8)
Endcapping: Fully Double End Capped
Particle Size: 3 µm
Pore Size: 100 Å
Column Dimensions: 4.0 mm ID x 100 mm
Length: 100 mm
Typical Flow Rate: 0.8–1.5 mL/min
Brand: Cogent
Special Order Item Information
For complete details, please review the Special Order Item Information.
Important Notes
Suitable for conventional HPLC systems
3 µm particles provide higher efficiency and sharper peaks than comparable 5 µm columns
Generates higher backpressure than larger particle columns
The 100 mm length provides greater resolution than 50 mm columns while maintaining practical run times
Particularly useful for long-chain fatty acid separations
Commonly used for hydrophobic and neutral compounds
Methods using longer columns and viscous mobile phases may approach instrument pressure limits
Commonly used as an alternative for USP L7 methods
This is a Special Order Item