HPLC Column, RP Phenyl, 10um, 4.0mm ID x 150mm Length, 100A. Cogent Brand. 1 EA.

Additional Information:

Cogent RP Phenyl is MICROSOLV's most popular phenyl stationary phase for reversed-phase HPLC and LC-MS applications. Manufactured with high-purity silica and a C3-phenyl bonded phase featuring exhaustive double endcapping, this column provides balanced hydrophobic retention combined with strong π-π interactions. The result is enhanced selectivity for aromatic, heteroaromatic, and moderately polar compounds that may not separate adequately on traditional C18 or C8 columns. The stationary phase is widely used in QC, GMP, research, and method development laboratories and is well suited as an alternative for USP L11 methods.

68024-15P-4 is an analytical HPLC column with dimensions of 4.0 mm ID x 150 mm length, packed with 10 µm RP Phenyl particles featuring a 100 Å pore size. The 150 mm column length provides enhanced resolving power and peak capacity for more demanding separations while maintaining reasonable analysis times. The C3-phenyl bonded phase provides improved selectivity for aromatic compounds through π-π interaction mechanisms while maintaining reproducible retention, excellent peak symmetry, reduced peak tailing, and lower silanol activity. The 10 µm particle size supports higher flow rates while generating lower backpressure than smaller particle columns. Typical flow rates are approximately 0.8–1.8 mL/min depending on mobile phase composition and system configuration.

This column is commonly used for aromatic pharmaceuticals, positional isomers, peptides, tocopherols, flavonoids, polynuclear aromatic compounds, nitro-aromatic compounds, APIs, natural products, and related compounds. It is particularly useful when structurally similar analytes co-elute on C18 columns or when additional aromatic selectivity is desired. The 150 mm length is ideal when increased resolution is needed for difficult separations while maintaining compatibility with preparative method scouting and method development workflows. This product is supplied as a Special Order Item manufactured specifically upon receipt of order.

Key Benefits

  • RP Phenyl stationary phase with C3-phenyl bonded chemistry

  • Strong π-π interaction selectivity

  • Fully double endcapped

  • High-purity silica support

  • Reduced silanol activity

  • Reduced peak tailing

  • Excellent peak symmetry

  • Suitable alternative for USP L11 methods

  • Compatible with HPLC and LC-MS

  • Excellent for aromatic and moderately polar compounds

Typical Applications

  • USP L11 methods

  • Positional isomer separations

  • Aromatic pharmaceutical compounds

  • Active pharmaceutical ingredient (API) analysis

  • Peptide separations

  • Tocopherol analysis

  • Flavonoid analysis

  • Polynuclear aromatic compound analysis

  • Nitro-aromatic compound analysis

  • Natural product analysis

Specifications

  • Product Type: HPLC Column

  • Stationary Phase: RP Phenyl

  • Chromatography Mode: Reversed Phase

  • USP Classification: L11

  • Bonded Phase: C3-Phenyl (Propyl Phenyl)

  • Endcapping: Fully Double Endcapped

  • Particle Size: 10 µm

  • Pore Size: 100 Å

  • Column Dimensions: 4.0 mm ID x 150 mm

  • Length: 150 mm

  • Typical Flow Rate: 0.8–1.8 mL/min

  • Brand: Cogent

Additional Resources

Special Order Item Information

Important Notes

  • Suitable as an alternative for USP L11 methods

  • Often selected when C18 or C8 columns do not provide sufficient selectivity

  • Excellent for aromatic and structurally similar compounds

  • Effective for peptides and moderately polar analytes

  • Commonly used in GMP, QC, and research laboratories

  • Longer column length provides increased resolution for complex separations

  • Frequently used for preparative method scouting and method development

  • A Cogent Column Filter is included and recommended to help protect the column and extend service life

  • Special Order Item


 

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