Process HPLC Column, RP C8 Octyl, Wide Pore, 10um, 300A. 50mm ID x 50mm Length. Cogent Brand. 1 EA.
Additional Information:
Cogent RP C8 Octyl Wide Pore is a reversed-phase process HPLC stationary phase manufactured using high-purity 300 Å silica with traditional octyl (C8) silane bonding and complete double endcapping. The wide pore structure is specifically designed to improve accessibility for proteins, peptides, and other large biomolecules while maintaining the moderate hydrophobicity and selectivity characteristic of C8 chemistry. This stationary phase is well suited for process-scale purification workflows where high recovery, efficient fraction collection, and loading capacity are critical.
68008-P50-50-3M is a process HPLC column with dimensions of 50 mm ID x 50 mm length, packed with 10 µm RP C8 Octyl Wide Pore particles featuring a 300 Å pore size. The extra-large internal diameter provides high sample loading capacity for production-scale purification, while the shorter 50 mm length is optimized for rapid purification cycles, high throughput processing, and process method optimization. The 10 µm particle size supports high flow rates with lower operating backpressure, making this column well suited for process development, pilot-scale production, and manufacturing applications. Typical operating flow rates are approximately 80–200 mL/min depending on sample load, mobile phase composition, and system capabilities.
Designed for purification and fraction collection rather than routine analytical HPLC, this column is particularly useful for proteins, peptides, enzymes, and other large biomolecules. The shorter column format is often selected when throughput and loading capacity are prioritized over maximum chromatographic resolution. Analytical methods are typically developed and optimized on analytical columns before transfer to preparative and process-scale columns such as this one. A specialized process HPLC system capable of high flow rates, large injection volumes, and large-scale fraction collection is required. This product is supplied as a Special Order Item manufactured specifically upon receipt of order.
Key Benefits
RP C8 Octyl Wide Pore stationary phase
300 Å pore size optimized for biomolecules
Fully double endcapped chemistry
Traditional octyl (C8) bonded phase
Designed for process-scale HPLC purification
High sample loading capacity
Excellent for proteins and peptides
10 µm particles for lower operating backpressure
Suitable for high process flow rates
Fast purification cycles with 50 mm length
Typical Applications
Process HPLC purification
Protein purification
Peptide purification
Enzyme purification
Biomolecule isolation
Biopharmaceutical manufacturing
Biotechnology production
Process development
Pilot plant operations
Large-scale fraction collection
Specifications
Product Type: Process HPLC Column
Stationary Phase: RP C8 Octyl Wide Pore
Chromatography Mode: Reversed Phase
Bonded Phase: Octyl (C8)
Endcapping: Fully Double Endcapped
Particle Size: 10 µm
Pore Size: 300 Å
Column Dimensions: 50 mm ID x 50 mm
Length: 50 mm
Typical Flow Rate: 80–200 mL/min
Brand: Cogent
Special Order Item Information
Important Notes
Intended for purification and fraction collection rather than routine analytical HPLC
Optimized for proteins, peptides, enzymes, and other large biomolecules
High loading capacity supports process-scale isolations
Short column length supports rapid purification cycles and process development
Analytical methods are often developed on analytical columns before transfer to preparative and process columns
Requires a process HPLC system capable of high flow rates and large-scale fraction collection
Special Order Item