Process HPLC Column, RP C8 Octyl, 10um, 100A. 50mm ID x 100mm Length. Cogent Brand. 1 EA.
Additional Information:
Cogent RP C8 Octyl is a reversed-phase process HPLC stationary phase manufactured using high-purity silica with traditional octyl (C8) silane bonding and complete double endcapping. The moderate hydrophobicity of the C8 ligand provides lower retention than C18 phases while maintaining effective retention of hydrophobic and neutral compounds. This selectivity makes the phase an excellent choice for process-scale purification where high recovery, throughput, and efficient fraction collection are critical.
68008-P50-100 is a process HPLC column with dimensions of 50 mm ID x 100 mm length, packed with 10 µm RP C8 Octyl particles featuring a 100 Å pore size. The extra-large internal diameter provides exceptionally high sample loading capacity for production-scale purification, while the 100 mm length offers an effective balance between throughput and purification efficiency. The 10 µm particle size supports high flow rates with lower operating backpressure, making this column well suited for process development, pilot-scale production, and manufacturing applications. Typical operating flow rates are approximately 80–200 mL/min depending on sample load, mobile phase composition, and system capabilities.
Designed for purification and fraction collection rather than routine analytical HPLC, this column is ideal for isolating hydrophobic or neutral compounds in pharmaceutical manufacturing, process chromatography, natural product purification, production support, and large-scale process development. Analytical methods are typically developed and optimized on analytical columns before transfer to preparative and process-scale columns such as this one. A specialized process HPLC system capable of high flow rates, large injection volumes, and large-scale fraction collection is required. This product is supplied as a Special Order Item manufactured specifically upon receipt of order.
Key Benefits
RP C8 Octyl stationary phase
Fully double endcapped chemistry
Traditional octyl (C8) bonded phase
Designed for process-scale HPLC purification
Exceptionally high sample loading capacity
Lower retention than C18 phases
10 µm particles for lower operating backpressure
Suitable for high process flow rates
Balanced throughput and purification efficiency
Ideal for large-scale purification and fraction collection
Typical Applications
Process HPLC purification
Large-scale fraction collection
Compound isolation
Pharmaceutical manufacturing
Process development
Production support purification
Natural product purification
Pilot plant operations
Method scale-up
Manufacturing chromatography
Specifications
Product Type: Process HPLC Column
Stationary Phase: RP C8 Octyl
Chromatography Mode: Reversed Phase
Bonded Phase: Octyl (C8)
Endcapping: Fully Double Endcapped
Particle Size: 10 µm
Pore Size: 100 Å
Column Dimensions: 50 mm ID x 100 mm
Length: 100 mm
Typical Flow Rate: 80–200 mL/min
Brand: Cogent
Special Order Item Information
Important Notes
Intended for purification and fraction collection rather than routine analytical HPLC
Exceptionally high loading capacity supports process-scale isolations
Analytical methods are often developed on analytical columns before transfer to preparative and process columns
Requires a process HPLC system capable of high flow rates and large-scale fraction collection
Provides less retention than comparable C18 phases
Special Order Item