Prep HPLC Column, RP C8 Octyl, 10um, 100A. 30mm ID x 50mm Length. Cogent Brand. 1 EA.
Additional Information:
Cogent RP C8 Octyl is a reversed-phase preparative HPLC stationary phase manufactured using high-purity silica with traditional octyl (C8) silane bonding and complete double endcapping. The moderate hydrophobicity of the C8 ligand provides lower retention than C18 phases while maintaining effective retention of hydrophobic and neutral compounds. This selectivity makes the phase an excellent choice for preparative purification workflows where high recovery, efficient fraction collection, and loading capacity are important.
68008-P30-50 is a preparative HPLC column with dimensions of 30 mm ID x 50 mm length, packed with 10 µm RP C8 Octyl particles featuring a 100 Å pore size. The extra-large internal diameter provides very high sample loading capacity for preparative-scale purification, while the shorter 50 mm length is optimized for rapid purification cycles, high throughput processing, and preparative method optimization. The 10 µm particle size supports higher flow rates with lower operating backpressure, making this column suitable for purification, process development, and scale-up workflows. Typical operating flow rates are approximately 30–80 mL/min depending on sample load, mobile phase composition, and system capabilities.
Designed for purification and fraction collection rather than routine analytical HPLC, this column is ideal for isolating hydrophobic or neutral compounds in pharmaceutical research, synthetic chemistry, natural product purification, reference standard preparation, and production-support applications. The shorter column format is often selected when throughput and loading capacity are prioritized over maximum chromatographic resolution. Analytical methods are typically developed using analytical columns before transfer and optimization on preparative columns such as this one. A specialized preparative HPLC system capable of higher flow rates, larger injection volumes, and fraction collection is required.
Key Benefits
RP C8 Octyl stationary phase
Fully double endcapped chemistry
Traditional octyl (C8) bonded phase
Designed for preparative HPLC purification
Very high sample loading capacity
Lower retention than C18 phases
10 µm particles for lower operating backpressure
Suitable for higher preparative flow rates
Fast purification cycles with 50 mm length
Ideal for purification and fraction collection
Typical Applications
Preparative HPLC purification
Fraction collection
Compound isolation
Pharmaceutical research
Synthetic chemistry
Natural product purification
Reference standard preparation
Process development
Method scale-up
Production support purification
Specifications
Product Type: Preparative HPLC Column
Stationary Phase: RP C8 Octyl
Chromatography Mode: Reversed Phase
Bonded Phase: Octyl (C8)
Endcapping: Fully Double Endcapped
Particle Size: 10 µm
Pore Size: 100 Å
Column Dimensions: 30 mm ID x 50 mm
Length: 50 mm
Typical Flow Rate: 30–80 mL/min
Brand: Cogent
Special Order Item Information
Important Notes
Intended for purification and fraction collection rather than routine analytical HPLC
Very high loading capacity supports large-scale preparative isolations
Short column length supports rapid purification cycles and process development
Analytical methods are often developed on analytical columns before transfer to preparative columns
Requires a preparative HPLC system capable of higher flow rates and fraction collection
Provides less retention than comparable C18 phases
Special Order Item