Prep HPLC Column, RP C8 Octyl, 10um, 100A. 21.2mm ID x 100mm Length. Cogent Brand. 1 EA.
Additional Information:
Cogent RP C8 Octyl is a reversed-phase preparative HPLC stationary phase manufactured using high-purity silica with traditional octyl (C8) silane bonding and complete double endcapping. The moderate hydrophobicity of the C8 ligand provides lower retention than C18 phases while maintaining effective retention of hydrophobic and neutral compounds. This selectivity makes the phase an excellent choice for preparative purification workflows where throughput, recovery, and efficient fraction collection are essential.
68008-P21-100 is a preparative HPLC column with dimensions of 21.2 mm ID x 100 mm length, packed with 10 µm RP C8 Octyl particles featuring a 100 Å pore size. The large internal diameter provides substantial sample loading capacity, while the 100 mm length offers an effective balance between purification efficiency and productivity. The 10 µm particle size supports higher flow rates with lower operating backpressure, making the column well suited for routine purification and scale-up workflows. Typical operating flow rates are approximately 15–40 mL/min depending on mobile phase conditions, sample load, and system capabilities.
Designed for purification and fraction collection rather than routine analytical HPLC, this column is ideal for isolating hydrophobic or neutral compounds in pharmaceutical research, synthetic chemistry, natural product purification, reference standard preparation, and process development applications. Analytical methods are typically developed on analytical columns before transfer and optimization on preparative columns such as this one. A specialized preparative HPLC system capable of higher flow rates, larger injection volumes, and fraction collection is required. This product is supplied as a Special Order Item manufactured specifically upon receipt of order.
Key Benefits
RP C8 Octyl stationary phase
Fully double endcapped chemistry
Traditional octyl (C8) bonded phase
Designed for preparative HPLC purification
High sample loading capacity
Lower retention than C18 phases
10 µm particles for lower operating backpressure
Suitable for higher preparative flow rates
Balanced throughput and resolution with 100 mm length
Ideal for purification and fraction collection
Typical Applications
Preparative HPLC purification
Fraction collection
Compound isolation
Pharmaceutical research
Synthetic chemistry
Natural product purification
Reference standard preparation
Process development
Method scale-up
Production support purification
Specifications
Product Type: Preparative HPLC Column
Stationary Phase: RP C8 Octyl
Chromatography Mode: Reversed Phase
Bonded Phase: Octyl (C8)
Endcapping: Fully Double Endcapped
Particle Size: 10 µm
Pore Size: 100 Å
Column Dimensions: 21.2 mm ID x 100 mm
Length: 100 mm
Typical Flow Rate: 15–40 mL/min
Brand: Cogent
Special Order Item Information
Important Notes
Intended for purification and fraction collection rather than routine analytical HPLC
High loading capacity supports preparative-scale isolations
Analytical methods are often developed on analytical columns before transfer to preparative columns
Requires a preparative HPLC system capable of higher flow rates and fraction collection
Provides less retention than comparable C18 phases
Special Order Item