HPLC Column, RP C8 Octyl, 10um, 4.6mm ID x 250mm Length, 100A. Cogent Brand. 1 EA.

Additional Information:

Cogent RP C8 Octyl is a reversed-phase HPLC stationary phase manufactured using high-purity silica with traditional octyl (C8) silane bonding and complete double endcapping. The moderate hydrophobicity of the C8 ligand provides an excellent balance between retention and elution strength, making it suitable for a broad range of hydrophobic and neutral compounds. This stationary phase is commonly selected as an alternative for USP methods that specify L7 column classifications and is frequently used when reduced retention compared to C18 phases is preferred.

68008-25P is an analytical HPLC column with dimensions of 4.6 mm ID x 250 mm length, packed with 10 µm RP C8 Octyl particles featuring a 100 Å pore size. The 250 mm length provides maximum resolving power and peak capacity within the analytical RP C8 column family, making it ideal for challenging separations involving closely related compounds. The 10 µm particle size provides lower operating backpressure while supporting reliable and reproducible analytical performance.

This column is well suited for analysis of hydrophobic and neutral compounds, including long-chain fatty acids and related analytes. The C8 stationary phase provides less retention than C18 columns, often reducing analysis times while maintaining excellent selectivity. The 250 mm format remains a preferred configuration in many established and validated methods that continue to be used in pharmaceutical, industrial, and quality control laboratories today.

Key Benefits

  • RP C8 Octyl stationary phase

  • Fully double endcapped chemistry

  • Traditional octyl (C8) bonded phase

  • Suitable alternative for USP L7 methods

  • Lower retention than C18 columns

  • 10 µm particles for lower operating backpressure

  • Maximum resolution with 250 mm length

  • High-purity silica support

  • Robust analytical performance

  • Commonly used in established legacy methods

Typical Applications

  • USP L7 methods

  • Long-chain fatty acid analysis

  • Hydrophobic compound analysis

  • Neutral compound analysis

  • Pharmaceutical analysis

  • Quality control testing

  • Method validation

  • Routine laboratory testing

  • Raw material analysis

  • Reversed-phase HPLC separations

Specifications

  • Product Type: Analytical HPLC Column

  • Stationary Phase: RP C8 Octyl

  • Chromatography Mode: Reversed Phase

  • USP Classification: L7

  • Bonded Phase: Octyl (C8)

  • Endcapping: Fully Double Endcapped

  • Particle Size: 10 µm

  • Pore Size: 100 Å

  • Column Dimensions: 4.6 mm ID x 250 mm

  • Length: 250 mm

  • Typical Flow Rate: 1.0–2.0 mL/min

  • Brand: Cogent

Special Order Item Information

Important Notes

  • Suitable as an alternative for USP L7 methods

  • Provides less retention than C18 stationary phases

  • Commonly used for long-chain fatty acid separations

  • Maximum column length provides enhanced resolving power and peak capacity

  • Frequently specified in legacy validated methods that remain in use today

  • Compatible with conventional HPLC systems

  • Special Order Item


 

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