CUSTOM ITEM: HPLC Column, Diamond Hydride, 4 um, 3.0 mm ID x 100 mm Length, 100 A. Cogent TYPE-C Brand. 1 EA.
Additional Info:
The 70000‑10P‑3 Diamond Hydride HPLC Column is a solvent‑efficient analytical column designed for high‑resolution separations of polar and mixed‑polarity compounds. Built on proven Cogent TYPE‑C™ silica hydride technology, this column delivers reliable retention, fast equilibration, and long column lifetime using conventional HPLC and LC‑MS instrumentation.
The 3.0 mm × 100 mm format provides increased resolution compared to shorter columns while maintaining lower solvent consumption than traditional 4.6 mm ID analytical columns. This makes it an excellent choice for routine analysis, method development, and regulated workflows where efficiency and reproducibility are critical.
This item is custom and can be manufactured to order.
Why This Column Is Used
The 3.0 mm internal diameter is widely adopted as a solvent‑saving alternative to standard analytical columns. This configuration offers:
Reduced mobile‑phase consumption
Improved efficiency compared to shorter column formats
Straightforward method scaling from 4.6 mm ID columns
Compatibility with standard HPLC and LC‑MS systems
The 100 mm length strikes a practical balance between speed and resolving power, making this column suitable for both routine and development work.
Diamond Hydride™ Stationary Phase Advantage
Manufactured using Cogent TYPE‑C™ silica hydride technology, the Diamond Hydride stationary phase provides important advantages over conventional bonded‑silica HILIC columns:
Faster equilibration, reducing downtime between injections
Stable and reproducible retention across a wide range of solvent compositions
Long column lifetime supporting routine analytical use
The silica hydride surface enables mixed‑mode retention mechanisms, allowing effective separation of analytes that are poorly retained by traditional reversed‑phase columns.
Typical Applications
This column is routinely used for:
Small, highly polar molecules
Amino acids and organic acids
Polar and mixed‑polarity peptides
Metabolites and other biologically relevant compounds
Routine HILIC and mixed‑mode analytical workflows
Efficient High‑Resolution Analysis
The 100 mm column length provides increased plate count and improved separation performance relative to shorter formats, making this column effective for:
Applications requiring additional resolution without excessive run times
Routine quantitative methods
Method development and validation
The solvent‑saving internal diameter improves efficiency while preserving analytical performance.
System Requirements
Typical operating flow rates: ~0.4–0.6 mL/min, depending on mobile‑phase viscosity and method conditions
Compatible with conventional analytical HPLC and LC‑MS systems
No specialized low‑flow hardware required
Flow rates and conditions may be optimized based on resolution requirements, pressure limits, and detector configuration.