Semi Prep HPLC Column, Phenyl Hydride, 4um, 100A. 10mm ID x 150mm Length, Preparative. Cogent TYPE-C Brand. 1 EA.
Additional Info:
Enhanced‑Resolution Semi‑Preparative HILIC Purification with Aromatic Selectivity Using Phenyl Hydride™
The 69020‑SP150 Phenyl Hydride™ Semi‑Preparative HPLC Column is designed for laboratories that require increased resolving power and retention during semi‑preparative purification of aromatic and polar compounds that are difficult to retain or separate using conventional reversed‑phase chromatography. Manufactured using Cogent TYPE‑C™ silica hydride technology, this stationary phase delivers excellent aromatic selectivity, fast equilibration, and robust column lifetime under semi‑preparative operating conditions.
This column format is selected when improved peak spacing, enhanced compound discrimination, or greater analytical confidence is required beyond shorter semi‑prep formats.
Why Choose Phenyl Hydride™ for Semi‑Preparative Aromatic Separations
Phenyl Hydride™ stationary phases combine HILIC‑type retention with interaction mechanisms favorable for aromatic compounds, making them particularly effective for semi‑preparative separations:
Strong retention of polar and moderately polar analytes under high‑organic mobile‑phase conditions
π–π and hydrophobic interactions that enhance aromatic selectivity
Improved separation of closely related or structurally similar compounds
Highly reproducible retention behavior across repeated injections
These characteristics make Phenyl Hydride™ especially valuable for isolations where purity and separation quality are critical.
Cogent TYPE‑C™ Silica Hydride Advantage
Phenyl Hydride™ columns are based on silica hydride surfaces rather than traditional silanol‑rich bonded silica, providing important performance advantages for semi‑preparative applications:
Faster equilibration compared to conventional bonded‑silica HILIC phases
Stable retention at high organic solvent composition
Reduced susceptibility to phase collapse or dewetting
Extended column lifetime under repetitive semi‑preparative use
These features support consistent performance and predictable separations during purification and method scale‑up.
Ideal Applications
The 69020‑SP150 Phenyl Hydride™ semi‑preparative column is routinely used for purification of:
Aromatic amines
Small peptides containing aromatic residues
Azides and heteroaromatic compounds
Polar analytes poorly retained by reversed‑phase methods
It is particularly effective when increased column length is required to resolve closely eluting compounds.
10 mm ID × 150 mm Length for Enhanced Semi‑Preparative Resolution
The 10 mm internal diameter × 150 mm length configuration provides:
Increased resolving power compared to 100 mm semi‑prep columns
Improved peak spacing for difficult separations
Higher sample‑loading capacity than analytical formats
This format is commonly selected when additional separation efficiency is needed without moving to full preparative diameters.
System Compatibility and Operating Requirements
Due to its diameter and operating profile, this column requires a specialized HPLC system capable of semi‑preparative operation, including:
Reliable delivery of elevated flow rates
Appropriate injector and detector configurations
Pressure and solvent handling suitable for larger‑ID columns
Typical flow‑rate range: Method‑dependent and governed by system capability System compatibility: Semi‑preparative or preparative‑capable HPLC systems Special requirements: Standard analytical‑only HPLC systems may not be suitable
Custom Order Manufacturing Notice
The 69020‑SP150 Phenyl Hydride™ Semi‑Preparative Column:
Can be manufactured to order
Is supplied according to Custom Order specifications
Is intended for users who have confirmed system compatibility and application fit
Customers are encouraged to review Custom Order information prior to purchase.