Catalog Number - 69020-P30-150

High‑Resolution Preparative HILIC Purification with Aromatic Selectivity Using Phenyl Hydride™

The 69020‑P30‑150 Phenyl Hydride™ Preparative HPLC Column is designed for laboratories requiring enhanced resolution and retention during preparative‑scale purification of aromatic and polar compounds that are difficult to retain using conventional reversed‑phase chromatography. Manufactured using Cogent TYPE‑C™ silica hydride technology, this stationary phase delivers excellent aromatic selectivity, reliable retention behavior, and robust column lifetime under demanding preparative conditions.

This column format is selected when longer column length is required to increase compound discrimination, improve peak spacing, or enhance purification confidence for closely related analytes.

Why Choose Phenyl Hydride™ for Preparative Aromatic Separations

Phenyl Hydride™ stationary phases combine HILIC‑type retention with interaction mechanisms that favor aromatic compounds, making them particularly effective at preparative scale:

• Strong retention of polar and moderately polar analytes under high‑organic mobile‑phase conditions

• π–π and hydrophobic interactions that enhance aromatic selectivity

• Improved separation of structurally similar or closely eluting compounds

• Highly reproducible retention behavior across repeated preparative injections

These characteristics make Phenyl Hydride™ ideal for preparative workflows where selectivity, purity, and resolution are critical.

Cogent TYPE‑C™ Silica Hydride Advantage

Unlike traditional bonded‑silica HILIC phases, Phenyl Hydride™ columns utilize silica hydride surfaces, offering important performance benefits for larger preparative column formats:

• Faster equilibration compared to conventional bonded‑silica phases

• Stable retention at high organic solvent compositions

• Reduced susceptibility to dewetting or phase collapse

• Extended column lifetime under repetitive high‑load purification conditions

These advantages support predictable performance and reliable scale‑up from analytical to preparative separations.

Ideal Applications

The 69020‑P30‑150 Phenyl Hydride™ preparative column is routinely used for purification of:

• Aromatic amines

• Small peptides containing aromatic residues

• Azides and heteroaromatic compounds

• Polar analytes that exhibit poor retention or resolution in reversed‑phase systems

It is especially valuable when increased column length is needed to resolve closely related compounds or improve purification margins.

30 mm ID × 150 mm Length for Enhanced Preparative Resolution

The 30 mm internal diameter × 150 mm length configuration provides:

• Increased resolving power compared to shorter preparative columns

• High sample‑loading capacity suitable for preparative workflows

• Improved peak spacing for difficult or closely related compounds

This format is commonly chosen when additional separation efficiency is required without transitioning to purification‑scale column diameters.

System Compatibility and Operating Requirements

Due to its size and operating requirements, this column requires a specialized preparative HPLC system capable of:

• Delivering high and stable flow rates

• Supporting preparative‑scale injectors and detector flow cells

• Operating within appropriate pressure and solvent limits

Typical flow‑rate range: Method‑dependent; determined by system capability and pressure constraints System compatibility: Preparative HPLC systems only Special requirements: Standard analytical HPLC systems are not suitable for this column size

Custom Order Manufacturing Notice

The 69020‑P30‑150 Phenyl Hydride™ Preparative Column is a Custom Order manufactured item:

• Can be manufactured to order

• Non‑returnable once an order is placed

• Not stocked inventory

Customers are advised to confirm system compatibility and application suitability prior to ordering.

• Read our Custom Item policy.