Prep HPLC Column, Phenyl Hydride, 4um, 100A. 30mm ID x 100mm Length, Preparative. Cogent TYPE-C Brand. 1 EA.
Additional Info:
Preparative‑Scale HILIC Purification with Aromatic Selectivity Using Phenyl Hydride™
The 69020‑P30‑100 Phenyl Hydride™ Preparative HPLC Column is designed for laboratories performing preparative‑scale purification of aromatic and polar compounds that are difficult to retain or resolve using conventional reversed‑phase chromatography. Manufactured with Cogent TYPE‑C™ silica hydride technology, this stationary phase provides excellent selectivity, faster equilibration relative to column size, and robust column lifetime under high‑load preparation conditions.
This column format is selected when purification methods require enhanced aromatic interaction mechanisms and reliable retention for compound classes that elute too early or co‑elute in reversed‑phase systems.
Why Choose Phenyl Hydride™ for Preparative Aromatic Separations
Phenyl Hydride™ stationary phases combine HILIC‑style retention with interaction mechanisms that are particularly effective for aromatic compounds at preparative scale:
Strong retention of polar and moderately polar analytes under high‑organic mobile‑phase conditions
π–π and hydrophobic interactions that improve selectivity for aromatic structures
Enhanced discrimination of closely related compounds during purification
Reproducible retention behavior across repeated preparative runs
These characteristics make Phenyl Hydride™ especially effective for preparative workflows where compound purity and selectivity are critical.
Cogent TYPE‑C™ Silica Hydride Advantage
Phenyl Hydride™ columns are based on silica hydride surfaces rather than traditional silanol‑rich bonded silica, providing important performance benefits for large‑diameter preparative columns:
Faster equilibration compared to conventional bonded‑silica HILIC phases
Stable retention at high organic solvent composition
Reduced risk of phase collapse or dewetting
Extended column lifetime under repetitive, high‑load purification conditions
These attributes support consistent, predictable performance for preparative method development and scale‑up.
Ideal Applications
The 69020‑P30‑100 Phenyl Hydride™ preparative column is commonly used for purification of:
Aromatic amines
Small peptides containing aromatic residues
Azides and heteroaromatic compounds
Polar analytes that are poorly retained or unresolved by reversed‑phase methods
It is particularly valuable for isolations where aromatic selectivity is required to achieve clean compound separation.
30 mm ID × 100 mm Length for Preparative Purification
The 30 mm internal diameter × 100 mm length configuration provides:
High sample‑loading capacity suitable for preparative workflows
Efficient separations with manageable backpressure at elevated flow rates
Scalable purification of milligram‑to‑gram‑level samples
This format is selected when throughput and robustness are required without unnecessary column length.
System Compatibility and Operating Requirements
Due to its size and operating demands, this column requires a specialized preparative HPLC system capable of:
Delivering high and stable flow rates
Supporting preparative‑scale injectors and detectors
Operating within appropriate pressure and solvent limits
Typical flow‑rate range: Method‑dependent, determined by system capability and pressure constraints System compatibility: Preparative HPLC systems only Special requirements: Standard analytical HPLC systems are not suitable for this column size
Custom Order Manufacturing Notice
The 69020‑P30‑100 Phenyl Hydride™ Preparative Column is a Custom Order manufactured item:
Produced to order
Non‑returnable once an order is placed
Not stocked inventory
Customers should confirm system compatibility and application requirements prior to ordering.