This items is made to order and is not returnable and order cannot be canceled.

CUSTOM ITEM: HPLC Column, Phenyl Hydride, 4um, 3.0mm ID x 50mm Length, 100A. Cogent TYPE-C Brand. 1 EA.

Additional Info:

Fast HILIC Performance with Aromatic Selectivity in a Solvent‑Saver Phenyl Hydride™ Format

The 69020‑05P‑3 Phenyl Hydride™ HPLC Column is engineered for laboratories requiring rapid HILIC separations, enhanced aromatic selectivity, and reduced solvent consumption using conventional analytical HPLC systems. Manufactured with Cogent TYPE‑C™ silica hydride technology, the Phenyl Hydride stationary phase delivers excellent selectivity, fast equilibration, and long column lifetime for analytes that are difficult to retain or resolve using traditional reversed‑phase methods.

This column is particularly effective for compounds where aromatic or heteroaromatic functionality plays a critical role in chromatographic behavior.

Why Choose Phenyl Hydride™ for HILIC Applications

Phenyl Hydride™ columns provide a unique interaction profile that combines classic HILIC retention with additional selectivity for aromatic analytes:

  • Strong retention of polar analytes under HILIC conditions

  • π–π and hydrophobic interactions that enhance separation of aromatic compounds

  • Improved resolution for analytes poorly retained by reversed‑phase columns

  • Fast equilibration and highly reproducible retention behavior

These properties make Phenyl Hydride an excellent choice for both routine analysis and method‑development workflows where aromatic selectivity is required.

Cogent TYPE‑C™ Silica Hydride Advantage

The Phenyl Hydride stationary phase is based on silica hydride surfaces rather than conventional silanol‑rich silica, providing important performance benefits:

  • Faster equilibration compared to bonded‑silica HILIC phases

  • Stable retention mechanisms at high organic mobile‑phase content

  • Reduced phase collapse and improved robustness

  • Extended column lifetime for routine analytical use

These characteristics support high reliability and minimal downtime in demanding laboratory environments.

Ideal Applications

The 69020‑05P‑3 Phenyl Hydride column is routinely selected for:

  • Aromatic amines

  • Small peptides containing aromatic residues

  • Azides and heteroaromatic compounds

  • Polar analytes that are difficult to retain or separate using reversed‑phase methods

It is especially valuable when additional aromatic selectivity improves separation confidence.

3.0 mm ID “Solvent‑Saver” Column for Fast Analysis

The 3.0 mm ID × 50 mm length configuration offers several practical advantages:

  • Run times comparable to standard 4.6 mm ID columns

  • Significantly reduced mobile‑phase consumption

  • Lower operating flow rates with reduced backpressure

  • No requirement for specialized low‑flow or UHPLC equipment

This format is ideal for laboratories seeking improved efficiency and solvent savings while maintaining straightforward system compatibility.

HPLC, UV, and LC‑MS Compatibility

This column is compatible with:

  • Conventional analytical HPLC systems

  • UV detection using standard flow cells

  • LC‑MS workflows where moderate analytical flow rates are preferred

The 3.0 mm internal diameter supports standard injection volumes and detector configurations without the constraints associated with narrow‑bore columns.

Operating Guidelines and System Requirements

  • Typical flow‑rate range: ~0.4–0.6 mL/min (method‑dependent)

  • System compatibility: All conventional analytical HPLC systems

  • Special requirements: None; no low‑flow capability required

Flow rates may be optimized based on resolution needs, solvent composition, and system pressure limits.

Custom Order Notice

This product is manufactured as a Custom Order. Custom Order items are made to order, non‑returnable, and cannot be canceled once an order has been placed. Please review Custom Order policies or contact Customer Service prior to purchasing.

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