Cogent RP Biphenyl, 5 um, 4.6 mm ID x 100 mm Length, 100 A. Cogent Brand. 1 EA.
Additional Info:
Enhance Selectivity for Aromatic Compounds with Cogent RP Biphenyl HPLC Columns!
The Cogent RP Biphenyl stationary phase delivers unique selectivity compared to traditional C18 phases by leveraging π‑π interactions between analytes and the biphenyl functionality. This makes it particularly powerful for separating structurally similar aromatic and moderately polar compounds that are often difficult to resolve using conventional reversed‑phase columns.
With 5 µm particles and a 100 Å pore size, this column offers reliable performance for routine analytical methods while maintaining excellent peak shape, reproducibility, and durability.
Why Choose RP Biphenyl?
Enhanced Aromatic Selectivity Ideal for compounds containing phenyl groups or conjugated systems, providing improved resolution of positional isomers and closely related impurities.
Improved Separation of Challenging Compounds Offers different retention mechanisms than C18, enabling better separation of polar aromatics, halogenated compounds, and drug metabolites.
Key Benefits
π‑π interaction selectivity ✅ Better resolution of aromatic compounds
Reversed‑phase versatility ✅ Suitable for a wide range of analytes
5 µm particle size ✅ Robust, reproducible performance for routine methods
100 Å pore size ✅ Ideal for small molecule analysis
Standard 4.6 mm ID format ✅ Widely compatible with HPLC systems
100 mm length ✅ Balanced speed and resolution
Typical Applications
Pharmaceutical Analysis Accurate quantification of APIs, degradants, and impurities, especially aromatic drug compounds
Environmental Testing Detection of pesticides, phenols, and other aromatic pollutants in water and soil
Food Safety Analysis of additives, preservatives, and contaminants with aromatic structures
General Analytical Chemistry Separation of structurally similar compounds where C18 selectivity is insufficient
HPLC Column Use‑Case Framework
100 mm Length ✅ Balanced performance for resolution and run time
4.6 mm ID (Standard Analytical) ✅
Typical flow rate: ~0.8–1.2 mL/min
Ideal for routine HPLC systems
Robust and widely compatible format for method development and QC
Flow rate may be adjusted based on mobile phase viscosity, temperature, and system pressure limits.
Important Notes
Designed for reversed‑phase HPLC methods
Provides alternative selectivity vs traditional C18 phases
Compatible with standard HPLC instrumentation
Suitable for routine and method development workflows