Cogent RP Diphenyl, 5um, 4.6mm ID x 250mm Length, 100A. Cogent Brand. 1 EA. .
Additional Info:
Enhance Selectivity for Aromatic and Halogenated Compounds with Cogent RP Diphenyl HPLC Columns!
68564‑25P utilizes a diphenyl stationary phase that provides strong π‑π interactions along with shape selectivity, offering different and often complementary retention compared to both C18 and biphenyl phases. The extended 250 mm length increases plate count and resolution, making it ideal for complex mixtures requiring high separation efficiency.
With 5 µm particle size and 100 Å pore size, this column delivers robust, reproducible performance for demanding analytical methods, particularly where improved selectivity for aromatic, halogenated, or structurally similar compounds is required.
Why Choose RP Diphenyl?
Enhanced π‑π and Shape Selectivity Provides strong interaction with aromatic rings and enhanced discrimination of positional isomers and structurally related compounds.
Improved Separation of Polar Aromatics and Halogenated Compounds Offers unique selectivity compared to C18 and Biphenyl phases, making it particularly effective for difficult separations involving substituted aromatics and analytes with electron-withdrawing groups.
Key Benefits
π‑π and shape selectivity ✅ Enhanced resolution of aromatic compounds
Alternative selectivity to C18 ✅ Expands method development flexibility
5 µm particle size ✅ Reliable, reproducible performance for routine methods
100 Å pore size ✅ Optimized for small molecule analysis
Standard 4.6 mm ID format ✅ Compatible with most HPLC systems
250 mm length ✅ Maximum resolution and peak capacity
Typical Applications
Pharmaceutical Analysis Accurate quantification of APIs, degradants, and impurities, especially aromatic and halogenated drug compounds
Environmental Testing Detection of pesticides, phenols, and substituted aromatics in complex environmental samples
Food Safety Analysis of additives, contaminants, and residues with aromatic structures
General Analytical Chemistry Separation of closely related compounds where C18 or Biphenyl phases do not provide sufficient resolution
HPLC Column Use‑Case Framework
250 mm Length ✅ Maximum resolution and peak capacity
Ideal for complex separations and impurity profiling
Increased run times compared to shorter column lengths
4.6 mm ID (Standard Analytical) ✅
Typical flow rate: ~0.8–1.2 mL/min
Ideal for routine HPLC systems
Widely compatible format for QC and method development
Flow rate may be adjusted based on mobile phase viscosity, column temperature, and system pressure limits.
Important Notes
Designed for reversed‑phase HPLC methods
Offers complementary selectivity vs C18 and Biphenyl phases
Longer column length increases resolution while extending run time
Compatible with standard HPLC instrumentation
Suitable for advanced method development and high‑resolution separations