Catalog Number - 58846-E-08-002

58846-E-08-002 ARE‑Applied Research Mobile Phase Inlet Filters are economy, biocompatible, all‑PTFE filtration devices designed for HPLC, UHPLC, and LC‑MS mobile phase delivery systems, delivering maximum solvent recovery, ultra‑low flow restriction, and reliable protection of critical system components.

These filters utilize a “Last Drop” flat bottom‑draw design, allowing nearly complete withdrawal of mobile phase from reservoir bottles—reducing solvent waste and supporting uninterrupted analytical performance in high‑volume workflows and long chromatographic runs.

Constructed entirely from PTFE, these filters provide excellent chemical resistance, low extractables, and compatibility with sensitive applications, while offering a cost‑effective alternative to more complex inlet filter configurations.

✅ Explore bulk pack options for higher‑volume purchasing and standardization

“Last Drop” Design – Maximum Solvent Utilization

• 22 mm flat filter geometry

• Sits at the lowest point in the reservoir bottle

• Draws solvent to near‑empty conditions

• Minimizes waste and prevents pump starvation

✅ Ideal for bulk solvent handling and extended analytical runs

✅ Improves efficiency and solvent cost management

10 µm PTFE Element – Ultra‑High Flow Capacity

• Filters particles ≥ 10 µm

• Protects:

  • Pump seals and check valves

  • Injection systems

  • Columns and detectors

• Larger pore size provides:

  • Maximum flow capacity

  • Minimal restriction

  • Longest service life among PTFE filter options

✅ Ideal for high‑flow systems and pre‑filtered solvents

All‑PTFE Construction – Maximum Chemical Compatibility

• Fully PTFE wetted surfaces

• No mixed‑material flow path

• Highly resistant to aggressive solvents and buffers

✅ Suitable for LC‑MS, pharmaceutical, and biocompatible workflows

Visual Inspection Advantage – White Filter Element

• White PTFE surface enhances visibility of trapped particles

• Enables quick contamination assessment

• Helps determine optimal replacement timing

✅ Supports proactive maintenance and consistent system performance

Tubing Compatibility – Flexible Integration

• Designed for 1/8" low‑pressure tubing systems

• Requires user‑configured tubing attachment

• Compatible with standard and custom solvent setups

✅ Ideal for flexible or simplified tubing configurations

Economy Design – Cost‑Effective Performance

• Simplified construction without integrated connectors

• Lower cost compared to advanced inlet filter designs

• Maintains:

  • High filtration efficiency

  • Maximum solvent recovery

  • Reliable system protection

✅ Ideal for budget‑conscious laboratories and high‑volume workflows

Performance Advantages – High‑Flow Chromatography Systems

Compared to smaller pore filters:

• Lowest restriction for maximum throughput

• Reduced clogging risk

• Stable solvent delivery at high flow rates

• Extended service intervals

✅ Aligns with best practices for high‑efficiency chromatography systems

System Compatibility & Use

Designed for use with:

• HPLC / UHPLC mobile phase systems

• LC‑MS solvent delivery setups

• 1/8" low‑pressure tubing configurations

• Standard mobile phase reservoir bottles

✅ Installs directly into mobile phase bottles for inline filtration

Typical Applications

• High‑flow HPLC mobile phase filtration

• Bulk solvent preparation and handling

• LC‑MS solvent protection

• Pre‑filtered solvent workflows

• Routine analytical and QC laboratories

• Long‑duration and unattended runs

• Integrated into original equipment manufacturer (OEM) product designs

Important Usage Notes

• Designed for low‑pressure systems only

• Requires compatible 1/8" tubing setup

• Ensure secure tubing connection during installation

• Inspect filter regularly and replace as needed