Catalog Number - 58846-E-02-005

58846-E-02-005 ARE‑Applied Research Mobile Phase Inlet Filters are economy, biocompatible, all‑PTFE filtration devices designed for HPLC, UHPLC, and LC‑MS mobile phase delivery systems, delivering high filtration efficiency and maximum solvent utilization at a lower cost point.

These filters use a “Last Drop” flat bottom‑draw design, enabling nearly complete withdrawal of solvent from reservoir bottles—reducing waste and supporting uninterrupted analytical runs.

Constructed entirely of PTFE, these filters provide exceptional chemical resistance, low extractables, and broad solvent compatibility, making them well‑suited for sensitive analytical workflows while allowing flexible tubing configurations.

✅ See pack of 2 options for smaller quantity purchasing flexibility

“Last Drop” Design – Maximum Solvent Utilization

• 22 mm flat filter geometry

• Sits at the lowest point in the bottle

• Draws solvent to near‑empty conditions

• Minimizes waste and reduces risk of pump starvation

✅ Ideal for high‑volume solvent use and long analytical sequences

✅ Improves efficiency and solvent cost management

2.5 µm PTFE Element – Biocompatible Filtration

• Filters particles ≥ 2.5 µm (commonly protects against ~2 µm+ particulates)

• Protects:

  • Pump seals and check valves

  • Injection systems

  • Columns and detectors

• PTFE media provides:

  • Broad chemical compatibility

  • Biocompatibility

  • Low adsorption and extractables

✅ Suitable for LC‑MS, pharmaceutical, and routine HPLC workflows

All‑PTFE Construction – Maximum Chemical Compatibility

• Fully PTFE wetted surfaces

• No mixed‑material fluid path

• Highly inert and resistant to aggressive solvents

✅ Ideal for high‑purity and sensitive analytical applications

Visual Inspection Advantage – White Filter Element

• White PTFE surface enhances visibility of trapped particles

• Enables quick contamination assessment

• Helps determine optimal replacement timing

✅ Supports proactive maintenance and consistent system performance

Tubing Compatibility – Flexible Integration

• Designed for 1/8" low‑pressure tubing systems

• Requires user‑configured tubing attachment

• Compatible with simple and custom solvent setups

✅ Ideal for labs requiring flexibility in tubing configuration

Performance Advantages – Economy Solution

• Lower cost compared to integrated connector designs

• Simplified construction without sacrificing filtration efficiency

• Maintains:

  • High flow capacity

  • Maximum solvent recovery

  • Reliable particulate protection

✅ Provides cost‑effective access to high‑performance inlet filtration

System Compatibility & Use

Designed for use with:

• HPLC / UHPLC mobile phase systems

• LC‑MS solvent delivery setups

• 1/8" low‑pressure tubing configurations

• Standard mobile phase reservoir bottles

✅ Installs directly into mobile phase bottles for inline filtration

Typical Applications

• HPLC mobile phase filtration (economy setups)

• LC‑MS solvent protection

• Budget‑conscious laboratories

• Routine analytical workflows

• High‑volume solvent usage environments

• Integrated into original equipment manufacturer (OEM) product designs

Important Usage Notes

• Designed for low‑pressure systems only

• Requires compatible 1/8" tubing setup

• Ensure secure tubing attachment during installation

• Inspect filter element regularly and replace as needed