Catalog Number - 58846-08-002

58846-08-002 ARE‑Applied Research Mobile Phase Inlet Filters are high‑capacity, biocompatible solvent filtration devices engineered for HPLC, UHPLC, and LC‑MS mobile phase delivery systems, providing maximum solvent recovery, ultra‑low flow restriction, and critical protection of system components.

These filters incorporate a “Last Drop” flat‑profile design, enabling nearly complete withdrawal of mobile phase from reservoir bottles—an important advantage for high‑throughput workflows, long analytical sequences, and large‑volume solvent use.

Each filter is constructed with a 10 µm PTFE filter element and an inert PEEK / PTFE wetted flow path, ensuring excellent chemical compatibility, minimal extractables, and stable performance across demanding analytical applications.

✅ Explore bulk purchasing options for lab standardization and high‑volume workflows

“Last Drop” Design – Maximum Solvent Utilization

• Wide 22 mm flat bottom‑draw geometry

• Designed to sit at the lowest point in the bottle

• Draws solvent to near‑empty conditions

• Minimizes waste and reduces risk of pump run‑dry

✅ Ideal for bulk solvent handling, long runs, and high‑volume applications

✅ Improves lab efficiency and solvent cost control

10 µm PTFE Element – Ultra‑High Flow Capacity

• Filters particles ≥ 10 µm

• Protects:

  • Pump seals and check valves

  • Injector systems

  • HPLC columns and detectors

• Larger pore size provides:

  • Maximum flow rates

  • Minimal restriction / lowest backpressure impact

  • Longest service life among filter options

✅ Ideal for high‑flow systems and pre‑filtered solvents

Visual Inspection Advantage – White Filter Element

• White PTFE surface enhances visibility of trapped particles

• Enables quick contamination assessment

• Helps determine when replacement is required

✅ Supports proactive maintenance and consistent system performance

PEEK / PTFE Flow Path – High Purity Performance

• Wetted components made from:

  • PEEK (polyether ether ketone)

  • PTFE (inert fluoropolymer)

• Provides:

  • Chemical inertness

  • Low extractables and leachables

  • Broad solvent compatibility

✅ Suitable for LC‑MS, analytical, and biocompatible workflows

1/16" Connector with ETFE Ferrule – Secure Integration

• Integrated 1/16" tubing connector

• Includes ETFE ferrule for non‑flanged tubing

• Provides secure, leak‑free connection

• No additional fittings required

✅ Enables fast and reliable low‑pressure system setup

Performance Advantages – High‑Flow Chromatography Systems

Compared to smaller pore filters:

• Lowest flow restriction in this product category

• Reduced clogging risk

• Improved solvent delivery stability

• Extended intervals between maintenance

✅ Ideal for high‑efficiency, high‑throughput laboratory environments

System Compatibility & Use

Designed for use with:

• HPLC / UHPLC mobile phase systems

• LC‑MS solvent delivery setups

• Low‑pressure tubing systems (1/16")

• Standard mobile phase reservoir bottles

✅ Installs directly into mobile phase bottles for inline filtration

Typical Applications

• High‑flow HPLC mobile phase filtration

• Bulk solvent preparation and transfer

• LC‑MS solvent protection

• Pre‑filtered solvent workflows

• Routine analytical laboratory operations

• Long‑duration and unattended runs

• Integrated into original equipment manufacturer (OEM) product designs

Important Usage Notes

• Designed for low‑pressure systems only

• Ensure proper tubing installation with included ferrule

• Inspect filter element periodically for buildup

• Replace when flow performance declines