Catalog Number - 58846-04-002

58846-04-002 ARE‑Applied Research Mobile Phase Inlet Filters are high‑performance, biocompatible solvent filtration devices engineered for HPLC, UHPLC, and LC‑MS mobile phase delivery systems, providing maximum solvent recovery, high throughput, and critical system protection.

These filters feature an advanced “Last Drop” bell‑shaped flat profile, which enhances contact with the bottom of the bottle and enables nearly complete use of mobile phase solvents—especially important for long analytical runs, overnight sequences, and high‑value solvents.

Each filter is constructed with a 2.5 µm PTFE filter element and an inert PEEK / PTFE wetted flow path, delivering excellent chemical compatibility, low extractables, and consistent performance in both standard and biocompatible workflows.

Advanced “Last Drop” Bell Design – Maximum Solvent Utilization

• 22 mm wide, bell‑shaped profile

• Optimized bottom contact for improved solvent access

• Draws solvent to near‑empty conditions

• Minimizes waste and prevents premature run interruption

✅ Ideal for long runs, high‑throughput labs, and solvent‑intensive methods

✅ Improves workflow efficiency and reproducibility

2.5 µm PTFE Element – Biocompatible Filtration

• Removes particulates ≥ 2.5 µm

• Protects:

  • Pump seals and check valves

  • Injector components

  • HPLC columns and detectors

• PTFE media provides:

  • Broad solvent compatibility

  • Biocompatibility for sensitive workflows

  • Low adsorption and extractables

✅ Ideal for LC‑MS, pharmaceutical, and bioanalytical applications

Visual Inspection Advantage – White Filter Element

• White PTFE surface allows easy visualization of trapped particles

• Enables fast assessment of contamination buildup

• Helps determine when replacement is required

✅ Supports proactive maintenance and consistent system performance

PEEK / PTFE Flow Path – High Purity Performance

• Wetted components made from:

  • PEEK (polyether ether ketone)

  • PTFE (inert fluoropolymer)

• Provides:

  • Chemical inertness

  • Minimal leachables

  • Stable solvent compatibility

✅ Suitable for high‑purity chromatography workflows

Tripod Connector – Universal, Tool‑Free Connection

• All‑PEEK tripod tubing connector

• Accepts:

  • 1/16" OD tubing

  • 1/8" OD tubing

• No ferrules or nuts required

• Simple push‑fit installation and removal

✅ Enables fast setup and flexible system configuration

Performance Advantages – Modern HPLC Operation

Compared to conventional inlet filters:

• Maximizes usable solvent volume

• Reduces risk of air entering pump systems

• Improves flow stability at low solvent levels

• Supports continuous, unattended runs

✅ Aligns with best practices for chromatography system protection

System Compatibility & Use

Designed for use with:

• HPLC / UHPLC mobile phase systems

• LC‑MS solvent delivery setups

• Low‑pressure tubing configurations (1/16" and 1/8")

• Standard mobile phase reservoir bottles

✅ Installs directly into mobile phase bottles for inline filtration

Typical Applications

• HPLC mobile phase filtration

• LC‑MS solvent protection

• Biocompatible analytical workflows

• High‑throughput laboratories

• Long‑duration and overnight runs

• Integrated into original equipment manufacturer (OEM) product designs

Important Usage Notes

• Designed for low‑pressure systems only

• Ensure tubing is properly seated for secure connection

• Inspect filter element regularly for buildup

• Replace when flow restriction increases