Catalog Number - 58846-03-005

58846-03-005 ARE‑Applied Research Mobile Phase Inlet Filters are high‑performance, biocompatible solvent filtration devices engineered for HPLC, UHPLC, and LC‑MS mobile phase delivery systems, offering high throughput, solvent efficiency, and critical instrument protection.

These filters feature a “Last Drop” flat‑profile design, allowing nearly complete use of solvent in reservoir bottles—an important benefit for long analytical runs, overnight sequences, and expensive mobile phases.

Constructed with a 2.5 µm PTFE filter element and an inert PEEK / PTFE wetted flow path, these filters deliver excellent chemical compatibility, low extractables, and stable analytical performance.

✅ Explore smaller pack size options for flexible purchasing and inventory control

“Last Drop” Design – Maximum Solvent Utilization

• Wide 22 mm flat filter geometry

• Positions at the lowest point in the bottle

• Draws solvent to near‑empty conditions

• Minimizes waste and avoids premature run interruption

✅ Ideal for long runs, high‑throughput labs, and high‑value solvents

✅ Improves workflow efficiency and solvent cost management

2.5 µm PTFE Element – Biocompatible Filtration

• Removes particles ≥ 2.5 µm

• Protects:

  • Pump seals and check valves

  • Injection systems

  • HPLC columns and detectors

• PTFE media offers:

  • Broad solvent compatibility

  • Biocompatibility for sensitive workflows

  • Low adsorption and low extractables

✅ Ideal for pharmaceutical, bioanalytical, and LC‑MS applications

Visual Inspection Advantage – White Filter Element

• White PTFE element improves visibility of trapped particles

• Enables quick inspection of contamination buildup

• Allows timely replacement to maintain optimal flow

✅ Supports proactive maintenance and consistent system performance

PEEK / PTFE Flow Path – High Purity Performance

• Wetted components made from:

  • PEEK (polyether ether ketone)

  • PTFE (inert fluoropolymer)

• Ensures:

  • Chemical inertness

  • Minimal leachables

  • Stable compatibility with aqueous and organic solvents

✅ Suitable for high‑purity chromatography workflows

1/8" Connector with ETFE Ferrule – High‑Flow Integration

• Integrated 1/8" tubing connector

• Includes ETFE ferrule for secure sealing

• Designed for non‑flanged low‑pressure tubing

• Provides leak‑free connection without additional fittings

✅ Ideal for higher flow rate systems and larger tubing configurations

Performance Advantages – Modern HPLC Operation

Compared to traditional inlet filters:

• Maximizes usable solvent volume

• Reduces risk of air entering pump systems

• Improves flow stability at low solvent levels

• Supports long, unattended analytical runs

✅ Aligns with current best practices for chromatography system protection

System Compatibility & Use

Designed for use with:

• HPLC / UHPLC mobile phase systems

• LC‑MS solvent delivery setups

• Low‑pressure tubing systems (1/8")

• Standard mobile phase reservoir bottles

✅ Installs directly into mobile phase bottles for inline filtration

Typical Applications

• HPLC mobile phase filtration

• LC‑MS solvent protection

• Biocompatible analytical workflows

• High‑throughput laboratories

• Long‑duration and overnight runs

• Integrated into original equipment manufacturer (OEM) product designs

Important Usage Notes

• Designed for low‑pressure systems only

• Ensure tubing is properly seated with ferrule

• Inspect filter element regularly for buildup

• Replace as flow restriction increases