Guard Column Starter Set, UDC Cholesterol, complete with 5 each 4.0 mm ID x 10 mm long cartridges packed with 4 um, 100 A phase and 1 each guard column holder. Cogent TYPE-C Brand. 1 EA.
Additional Info:
The 69069‑PG4 Cogent UDC‑Cholesterol Guard Column Starter Set is a complete protection system for standard‑flow analytical HPLC columns, designed to preserve unique shape‑selective separations while extending column lifetime.
This starter kit includes:
(5) UDC‑Cholesterol guard cartridges
4.0 mm ID × 10 mm length
Packed with 4 µm, 100 Å TYPE‑C™ silica hydride UDC‑Cholesterol phase
Each cartridge is individually packaged in a protective Delrin™ case, preventing contamination, drying, and physical damage prior to use.
The included holder is compatible with all Cogent TYPE‑C™ guard cartridges, allowing flexibility across multiple stationary phases.
Designed for Standard Analytical Column IDs
This starter kit is optimized for:
3.0 mm ID solvent‑saving analytical columns
4.0 mm ID analytical columns
4.6 mm ID standard analytical HPLC columns
Ideal for conventional HPLC systems, ensuring:
Minimal band broadening
Maintained chromatographic efficiency
Consistent method performance
Why Use a Guard Column Starter Kit
Analytical columns are routinely exposed to:
Particulates and system contamination
Strongly retained compounds
Sample matrix buildup
Progressive column fouling
The 69069‑PG4 starter kit provides a sacrificial protection layer, helping to:
Extend analytical column lifetime significantly
Maintain consistent chromatographic performance
Reduce system downtime and replacement costs
Improve reproducibility across runs
Under typical use, the five included cartridges often provide sufficient protection for the full working life of an analytical column, depending on sample cleanliness.
UDC‑Cholesterol™ Guard Phase Advantages
Using the same stationary phase as your analytical column ensures:
Matched shape selectivity and retention behavior
No disruption to method performance
Seamless analyte transfer to the main column
Shape‑Selective Interaction
Separates compounds based on 3D molecular structure and steric fit
Ideal for isomers and closely related compounds
Strong Hydrophobic Retention
Effective for lipids and hydrophobic analytes
Enhances retention of difficult compounds
Tunable Selectivity
Modify separations using:
Temperature changes
Mobile phase composition
Cogent TYPE‑C™ Technology Benefits
Silica Hydride Surface
Direct Si–C bonding (no end‑capping required)
Reduced silanol interactions
Improved peak shape for basic and polar analytes
Faster Equilibration
Reduced cycle times
Increased analytical throughput
Durability
Resistant to hydrolysis
Long cartridge and column lifetime
Stable under demanding analytical conditions
Typical Applications
Standard analytical HPLC workflows
Steroidal compound analysis
Structural isomer separations
Lipids and hydrophobic compounds
Peptides, proteins, and oligonucleotides
Methods requiring shape‑selectivity protection