Guard Column cartridges, UDC Cholesterol, replacement, 2.0 mm ID x 10 mm long cartridges packed with 4 um, 100 A phase. Cogent TYPE-C Brand. 5/PK.
Additional Info:
The 69069‑PG2 Cogent UDC‑Cholesterol Guard Column Cartridges are replacement cartridges designed to protect analytical HPLC columns while preserving the unique shape‑selective performance of the UDC‑Cholesterol stationary phase.
Each cartridge is:
2.0 mm ID × 10 mm length
Packed with 4 µm, 100 Å TYPE‑C™ silica hydride UDC‑Cholesterol phase
Constructed in stainless steel housings with SS frits
Cartridges are individually packaged in protective Delrin™ cases, preventing contamination, drying, and damage before use.
⚠️ Requires guard column holder (sold separately)
Designed for 2.1 mm Analytical Columns
These cartridges are optimized for:
2.1 mm ID analytical HPLC columns
LC‑MS and low‑flow workflows
High‑sensitivity analytical methods
Proper guard column matching ensures:
Minimal impact on peak shape
Maintained chromatographic efficiency
Consistent retention and selectivity
Why Use Replacement Guard Cartridges
Analytical columns are routinely exposed to:
Particulates from samples and solvents
Strongly retained or irreversible contaminants
Matrix buildup from complex samples
Chemical fouling and degradation
The 69069‑PG2 cartridges act as a sacrificial protection layer, helping to:
Extend analytical column lifetime
Maintain consistent chromatographic performance
Reduce downtime and replacement costs
Improve reproducibility across runs
Cartridges can be replaced quickly without disturbing the analytical column.
UDC‑Cholesterol™ Guard Phase Advantages
Using the same stationary phase as your analytical column ensures:
Matched shape selectivity and retention behavior
No change in method performance
Seamless analyte transfer
Shape‑Selective Interaction
Separates analytes based on 3D molecular structure and steric fit
Ideal for isomers and closely related compounds
Strong Hydrophobic Retention
Effective for lipids and hydrophobic analytes
Enhances retention of difficult compounds
Tunable Selectivity
Adjust separation using:
Temperature changes
Mobile phase composition
Cogent TYPE‑C™ Technology Benefits
Silica Hydride Surface
Direct Si–C bonding (no end‑capping required)
Reduced silanol activity
Improved peak shape for basic and polar analytes
Faster Equilibration
Reduced cycle times
Increased analytical throughput
Durability
Resistant to hydrolysis
Long cartridge lifetime
Stable under demanding analytical conditions
Typical Applications
LC‑MS analytical methods
Steroidal compound analysis
Structural isomer separations
Lipids and hydrophobic analytes
Peptides, proteins, and oligonucleotides
Methods requiring shape‑selectivity protection