Guard Column Starter Set, Phenyl Hydride, complete with 5 each 4.0 mm ID x 10 mm long cartridges packed with 4 um, 100 A phase and 1 each guard column holder. Cogent TYPE-C Brand. 1 EA.

Additional Info:

Phenyl Hydride™ Guard Column Starter Set for Broad Analytical Column Protection

The 69020‑PG4 Phenyl Hydride™ Guard Column Starter Set provides a complete, ready‑to‑use solution for protecting analytical Phenyl Hydride™ HPLC columns across multiple internal diameters. Designed around Cogent TYPE‑C™ silica hydride technology, this starter set helps maintain chromatographic performance, preserve retention stability, and extend analytical column lifetime in routine HILIC workflows.

Guard columns are strongly recommended for applications involving complex sample matrices, frequent injections, or extended analytical sequences.

What’s Included in the Starter Set

This comprehensive starter kit includes:

  • Stainless Steel Guard Cartridge Column Holder Precision‑manufactured to provide secure, low‑dead‑volume installation upstream of the analytical column. The holder is compatible with Cogent TYPE‑C™ guard cartridges.

  • Five Phenyl Hydride™ Guard Cartridges Each cartridge is packed with 4 µm, 100 Å Phenyl Hydride™ stationary phase, matched to analytical Phenyl Hydride columns to maintain consistent selectivity and retention behavior.

Each guard cartridge is shipped in an individual, closeable Delrin® storage case to prevent drying, contamination, or mechanical damage prior to use.

Why Use Phenyl Hydride™ Guard Columns

Using matched Phenyl Hydride guard cartridges provides several important benefits:

  • Protects analytical columns from particulates and irreversibly adsorbed contaminants

  • Preserves peak shape, retention reproducibility, and column efficiency

  • Extends analytical column service life and reduces replacement frequency

  • Supports consistent performance over extended analytical runs

Under typical laboratory conditions, the included cartridges are often sufficient to protect an analytical column for the majority of its usable lifetime.

Phenyl Hydride™ Stationary Phase Consistency

The guard cartridges in this starter set are packed with the same Phenyl Hydride™ stationary phase chemistry used in analytical columns, ensuring:

  • No change in chromatographic selectivity or elution order

  • Minimal added dead volume

  • Seamless integration into existing HILIC methods

  • Stable retention under high‑organic mobile‑phase conditions

This phase consistency is critical to maintaining method integrity when guard protection is added.

Intended Use and Compatibility

The 69020‑PG4 Guard Column Starter Set is designed for use with:

  • 3.0 mm, 4.0 mm, and 4.6 mm ID analytical Phenyl Hydride™ columns

  • HILIC‑mode analytical HPLC workflows

  • Conventional analytical HPLC systems

The guard column holder installs directly upstream of the analytical column and supports straightforward cartridge replacement.

Guard Cartridge Replacement Guidance

Guard cartridges should be replaced when:

  • System backpressure increases

  • Peak shape begins to degrade

  • Retention behavior changes

  • Sample matrix complexity increases

Routine replacement ensures continued protection and consistent analytical performance.

 

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