Catalog Number - 69020-PG2

Phenyl Hydride™ Replacement Guard Cartridges for Analytical Column Protection

The 69020‑PG2 Phenyl Hydride™ Guard Column Replacement Cartridges are designed to protect analytical Phenyl Hydride™ HPLC columns from particulate matter and strongly retained contaminants that can degrade column performance. Packed with Phenyl Hydride™ stationary phase using Cogent TYPE‑C™ silica hydride technology, these guard cartridges help maintain retention stability, peak shape, and column efficiency during routine HILIC analysis.

Replacement cartridges are essential for preserving analytical column lifetime in workflows involving complex matrices, frequent injections, or extended usage. A compatible guard column holder is required and is sold separately

Why Use Phenyl Hydride™ Guard Cartridges

Using matched guard cartridges provides several important benefits:

• Protects analytical columns from particulates and irreversibly adsorbed contaminants

• Preserves chromatographic selectivity, peak shape, and retention consistency

• Extends analytical column lifetime and reduces replacement frequency

• Supports reproducible performance across extended analytical sequences

These cartridges serve as a sacrificial protection stage, capturing contaminants before they reach the analytical column.

High‑Quality Construction and Handling

Each guard cartridge in the 69020‑PG2 pack is:

• Packed in durable stainless‑steel tubing with stainless‑steel frits

• Filled with 4 µm, 100 Å Phenyl Hydride™ stationary phase

• Clearly labeled for identification and traceability

To prevent drying, contamination, or physical damage, each cartridge is shipped in an individual, closeable black Delrin® storage case.

Phenyl Hydride™ Stationary Phase Consistency

These guard cartridges use the same Phenyl Hydride™ stationary phase chemistry as corresponding analytical columns, ensuring:

• No change in chromatographic selectivity or elution order

• Minimal added dead volume

• Seamless integration into existing HILIC methods

• Stable performance under high‑organic mobile‑phase conditions

Phase consistency is critical for maintaining method integrity when guard protection is employed.

Intended Use and Compatibility

The 69020‑PG2 replacement guard cartridges are designed for use with:

• 2.1 mm ID analytical Phenyl Hydride™ columns

• HILIC‑mode analytical HPLC and LC‑MS workflows

A compatible guard column holder is required and is sold separately. Guard cartridges are installed directly upstream of the analytical column.

Replacement Guidance

Guard cartridges should be replaced when any of the following occur:

• Backpressure increases noticeably

• Peak shape begins to deteriorate

• Retention shifts are observed

• Sample cleanliness or matrix complexity changes

Routine replacement ensures continued protection and consistent analytical performance.