Guard Column Cartridges, NP Silica Wide Pore, 3um, 300A. 2.1mm ID x 10mm Length. Cogent Brand. 5/PK.

Additional Information:

Cogent NP Silica™ Wide Pore Guard Column Cartridges are designed to protect valuable analytical HPLC columns from particulate contamination, strongly retained compounds, and sample matrix components that can reduce column performance and shorten column life. Packed with ultra-high purity, low metal content 300Å NP Silica™ stationary phase that is not chemically modified, these guard cartridges provide the same selectivity characteristics as the analytical column while acting as a sacrificial protection device.

82361-PG1-3 Guard Column Cartridges are packed with 3 µm NP Silica™ Wide Pore media in a 2.1 mm ID x 10 mm format specifically designed for use with 2.1 mm ID analytical columns. The 300Å wide pore structure provides improved accessibility for larger molecules while protecting the analytical column from contaminants and particulates that can irreversibly adsorb to the stationary phase. Routine use helps maintain column efficiency, reproducibility, and retention characteristics while reducing replacement costs.

NP Silica™ Wide Pore guard cartridges are commonly used with HILIC and Normal Phase chromatography methods involving proteins, peptides, biomolecules, and other large hydrophilic or polar compounds. The matching stationary phase chemistry minimizes changes in chromatographic selectivity while extending analytical column lifetime. For proper installation and operation, these cartridges must be used with a compatible Cogent Guard Column Holder.

Key Benefits

  • NP Silica™ Wide Pore stationary phase

  • USP L3 equivalent chemistry

  • Ultra-high purity silica

  • Low metal content silica

  • Unmodified silica surface

  • 300Å wide pore design

  • 3 µm particle size

  • Protects analytical columns from contamination

  • Extends analytical column life

  • Compatible with 2.1 mm ID columns

Typical Applications

  • HILIC chromatography

  • Normal Phase HPLC

  • USP L3 methods

  • Protein analysis

  • Peptide analysis

  • Biomolecule separations

  • Large molecule analysis

  • Column protection

  • Method development

  • Pharmaceutical and biotechnology analyses

Specifications

  • Product Type: Guard Column Cartridges

  • Stationary Phase: NP Silica™ Wide Pore

  • USP Classification: L3

  • Particle Size: 3 µm

  • Pore Size: 300Å

  • Cartridge Dimensions: 2.1 mm ID x 10 mm

  • Quantity: 5 Cartridges per Pack

  • Cartridge Housing: Stainless Steel

  • Frit Material: Stainless Steel Frits with PEEK Frit Caps

  • Brand: Cogent

Required Guard Column Holder

Important Notes

  • Designed for 2.1 mm ID NP Silica™ Wide Pore analytical columns

  • Suitable for HILIC and Normal Phase chromatography

  • USP L3 equivalent chemistry

  • Unmodified silica stationary phase

  • Low metal content, high-purity silica

  • Wide pore 300Å silica provides improved accessibility for larger molecules

  • Protects analytical columns from particulates and strongly retained contaminants

  • Helps extend analytical column lifetime

  • Maintains method reproducibility and chromatographic performance

  • Must be used with a Cogent Guard Column Holder (83200-GH)

  • Supplied as a pack of 5 cartridges


 

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