Syringe Filters, 25mm, Polypropylene, 0.45um Pore Size. Peach Polypropylene, AQ Brand. 50/PK.

Additional Info:

The 58045-PP25-A AQ™ Syringe Filters are pharmaceutical-grade polypropylene membrane filters designed for HPLC sample preparation and dissolution testing in regulated laboratory environments. Featuring a 0.45 µm polypropylene (PP) membrane, these filters provide broad chemical compatibility, low extractables, and consistent chromatographic performance.

Polypropylene membranes are naturally hydrophilic with minimal conditioning required, making them an excellent choice for both aqueous and organic solvents, including acids and bases. This versatility makes them ideal for general-purpose filtration across diverse applications.

✅ Critical Compliance Advantage (No Flush Required)

Validated to meet key regulatory standards:

  • US FDA CFR Title 21, Part 210.3(b)(6) – minimum fiber release

  • USP <788> – particulate matter in injectables

  • USP “Sterile Water for Injection”

Benefits:

  • ✅ No initial flushing required

  • ✅ No 200 µL discard required

  • ✅ Extractable-free from first filtrate

  • ✅ Reduces risk of failed methods


Performance & Design

The 0.45 µm pore size is optimized for sample clarification and prefiltration, delivering reliable flow and particulate removal.

The polypropylene membrane provides excellent chemical resistance, supporting use with aqueous solutions, organic solvents, acids, and bases.

The 25 mm format is designed for larger sample volumes, making it ideal for routine and high-throughput workflows.

The 16-channel outlet design minimizes back pressure, allowing smooth filtration with reduced manual effort.

The peach housing allows quick identification, and each pack includes a Certificate of Analysis.


Key Features

0.45 µm Polypropylene Membrane (Pharma Grade)

  • Broad chemical compatibility

  • Suitable for aqueous and organic systems

✅ No Initial Flush Required (Validated)

  • No 200 µL discard required

Low Conditioning Requirement

  • Minimal preparation needed

  • Consistent performance from first filtrate

High Chemical Resistance

  • Compatible with solvents, acids, and bases

High Throughput (25 mm)

  • Handles larger sample volumes

Reduced Back Pressure

  • 16-channel outlet design

Low Extractables

  • Clean chromatographic results

Regulatory Compliance

  • FDA CFR 21, USP <788>

Color-Coded (Peach)

  • Identifies PP filters


Typical Applications

  • HPLC & UHPLC Sample Preparation – general-purpose filtration

  • Dissolution Testing – pharmaceutical QC

  • Organic & Aqueous Samples – versatile compatibility

  • Chemical Analysis – acids, bases, solvents

  • Routine Laboratory Workflows – high-throughput use


Specifications

  • Membrane Material: Polypropylene (PP)

  • Pore Size: 0.45 µm

  • Diameter: 25 mm

  • Housing: Polypropylene (PP)

  • Color Code: Peach

  • Chemical Compatibility: Aqueous, organic, acids, bases

  • Hydrophilicity: Hydrophilic (low conditioning)

  • Extractables: None detectable (no flush required)

  • Sterilization: Autoclave or EO

  • Compliance: FDA CFR 21, USP <788>

  • Pack Size: 50/PK

  • Brand: AQ™


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