Catalog Number - PQA-HOX-01

he PQA‑HOX‑01 Wavelength Calibration Solution is a NIST‑traceable Holmium Oxide (HOX) standard, designed for precise calibration and verification of wavelength accuracy in HPLC UV detectors and UV‑Vis spectrophotometers.

This solution can be used as a direct replacement for HSQ™, PQ™, or UV‑Vis qualification kits, or as a standalone calibration standard for routine instrument verification and compliance workflows.

Prepared as 4% holmium oxide in 10% perchloric acid, this certified solution provides reliable, repeatable absorbance characteristics across key UV wavelengths.

Holmium Oxide – Primary Wavelength Calibration Standard

• Internationally recognized primary wavelength calibration standard

• Supported by NIST and global regulatory organizations

• Provides 14 certified absorbance peaks

Certified Wavelength Range

• 241 nm to 640 nm

✅ Enables accurate wavelength verification across UV‑Vis detection range

Extended Calibration Capability

• When used with caffeine standards, enables calibration down to:

  • 205 nm

✅ Supports low‑wavelength UV detector validation for advanced analytical methods

Performance Qualification Applications

Used for calibration and verification of:

• Wavelength accuracy

• Detector performance

• UV‑Vis spectrophotometer validation

• HPLC UV detector qualification

✅ Critical for USP <1058> instrument qualification and AIQ compliance

Compatibility & Use Cases

• Fully compatible with:

  • HSQ™ Qualification Kits

  • PQ™ Qualification Kits

  • UV‑Vis qualification systems

• Also suitable as:

  • Standalone calibration solution

  • Routine performance verification tool

NIST Traceability & Compliance

• Manufactured to NIST SRM‑equivalent standards (SRM‑02034)

• Provides traceable, reproducible absorbance values

• Supports audit‑ready calibration documentation

✅ Essential for regulated laboratories and GMP environments

Shelf Life & Handling

• Supplied with minimum 6‑month shelf life upon delivery

• Two‑year expiration from date of manufacture

• Designed for frequent use in qualification workflows

✅ Ensures consistent performance in routine calibration programs

Workflow Advantages

Accurate Detector Calibration

• Ensures reliable wavelength accuracy verification

• Improves data quality and analytical confidence

Continuous Compliance

• Supports USP <1058> and AIQ requirements

• Maintains instruments in a qualified state between audits

Flexible Use

• Works as replacement or standalone solution

• Integrates easily into existing qualification workflows

Typical Applications

• HPLC wavelength calibration

• UV‑Vis spectrophotometer calibration

• USP <1058> compliance programs

• Analytical Instrument Qualification (AIQ)

• Pharmaceutical QC and validation labs

• Routine detector verification

Important Usage Notes

• Designed for UV detector and spectrophotometer calibration

• Use according to validated SOPs for qualification workflows

• Combine with standards (e.g., caffeine) for extended wavelength validation

• Store per recommended conditions to maintain solution integrity