HPLC Column, NP Cyano, 5um, 4.6mm ID x 250mm Length, 100A. Cogent Brand. 1 EA.
Additional Information:
Cogent NP Cyano™ HPLC Columns are designed for normal-phase chromatography of polar compounds requiring the selectivity associated with USP L10 classified stationary phases. Manufactured using ultra-high purity silica bonded with a three-carbon ligand containing a terminal cyano (CN) functional group, this non-endcapped stationary phase provides unique selectivity that often produces shorter retention times and faster column equilibration compared to unmodified silica columns.
82534-25P is packed with 5 µm NP Cyano™ particles featuring a 100 Å pore size in a 4.6 mm ID x 250 mm format. The 5 µm particle size provides excellent chromatographic performance while maintaining lower operating backpressures than smaller particle columns. The 250 mm column length delivers maximum resolution and peak capacity, making it ideal for challenging separations and complex sample matrices.
The 4.6 mm ID x 250 mm format is well suited for normal-phase chromatography of polar compounds, pharmaceutical analysis, quality control testing, and advanced method development. Typical flow rates are approximately 0.8-1.5 mL/min depending on mobile phase composition and application requirements.
Key Benefits
NP Cyano™ stationary phase
USP L10 equivalent chemistry
Ultra-high purity silica support
Non-endcapped surface
Three-carbon cyano bonded phase
100 Å pore size
Suitable for normal-phase chromatography
Shorter retention than unmodified silica columns
Faster equilibration between runs
Maximum chromatographic resolution
Typical Applications
Normal-phase HPLC
Polar compound analysis
Pharmaceutical analysis
Quality control testing
Method development
Chemical analysis
Organic compound separations
USP L10 method replacement
Routine analytical HPLC
Complex sample separations
Specifications
Product Type: HPLC Column
Stationary Phase: NP Cyano™
Chromatography Mode: Normal Phase
USP Classification: L10
Functional Group: Cyano (CN)
Particle Size: 5 µm
Pore Size: 100 Å
Column Dimensions: 4.6 mm ID x 250 mm
Recommended Flow Rate: 0.8-1.5 mL/min
Column Hardware: Stainless Steel
Brand: Cogent
Important Notes
Designed for normal-phase chromatography
USP L10 equivalent chemistry
Non-endcapped bonded phase
Provides shorter retention times than unmodified silica columns in many methods
Faster equilibration between runs compared to silica columns
Excellent choice for polar compound separations
Packed and shipped in normal-phase solvents
250 mm length provides maximum resolution and peak capacity
Compatible with most standard HPLC systems
For Cyano columns packed in reversed-phase solvents, see the Cogent RP Cyano product line