HPLC Column, NP Cyano, 5um, 2.1mm ID x 150mm Length, 100A. Cogent Brand. 1 EA.

Additional Information:

Cogent NP Cyano™ HPLC Columns are designed for normal-phase chromatography of polar compounds requiring the selectivity associated with USP L10 classified stationary phases. Manufactured using ultra-high purity silica bonded with a three-carbon ligand containing a terminal cyano (CN) functional group, this non-endcapped stationary phase provides unique selectivity that often produces shorter retention times and faster column equilibration compared to unmodified silica columns.

82534-15P-2 is packed with 5 µm NP Cyano™ particles featuring a 100 Å pore size in a 2.1 mm ID x 150 mm format. The narrow internal diameter reduces solvent consumption while maintaining the selectivity and performance expected from a USP L10 cyano phase. The 150 mm column length provides increased chromatographic resolution and peak capacity, making it well suited for more demanding separations and method development applications.

The 2.1 mm ID x 150 mm format is well suited for normal-phase chromatography of polar compounds, pharmaceutical analysis, quality control testing, and method development. Typical flow rates are approximately 0.2-0.3 mL/min. Standard HPLC systems used with 2.1 mm ID columns must be capable of delivering stable and reproducible low flow rates for optimum chromatographic performance.

Key Benefits

  • NP Cyano™ stationary phase

  • USP L10 equivalent chemistry

  • Ultra-high purity silica support

  • Non-endcapped surface

  • Three-carbon cyano bonded phase

  • 100 Å pore size

  • Suitable for normal-phase chromatography

  • Shorter retention than unmodified silica columns

  • Faster equilibration between runs

  • Reduced solvent consumption

Typical Applications

  • Normal-phase HPLC

  • Polar compound analysis

  • Pharmaceutical analysis

  • Quality control testing

  • Method development

  • Chemical analysis

  • Organic compound separations

  • USP L10 method replacement

  • Routine analytical HPLC

  • Complex sample separations

Specifications

  • Product Type: HPLC Column

  • Stationary Phase: NP Cyano™

  • Chromatography Mode: Normal Phase

  • USP Classification: L10

  • Functional Group: Cyano (CN)

  • Particle Size: 5 µm

  • Pore Size: 100 Å

  • Column Dimensions: 2.1 mm ID x 150 mm

  • Recommended Flow Rate: 0.2-0.3 mL/min

  • Column Hardware: Stainless Steel

  • Brand: Cogent

Important Notes

  • Designed for normal-phase chromatography

  • USP L10 equivalent chemistry

  • Non-endcapped bonded phase

  • Provides shorter retention times than unmodified silica columns in many methods

  • Faster equilibration between runs compared to silica columns

  • Excellent choice for polar compound separations

  • Packed and shipped in normal-phase solvents

  • 150 mm length provides increased resolution and peak capacity

  • Standard HPLC systems must be capable of reliable low-flow operation at approximately 0.2-0.3 mL/min

  • For Cyano columns packed in reversed-phase solvents, see the Cogent RP Cyano product line


 

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