HPLC Column, HPS Cyano, 5um, 4.6mm ID x 250mm Length, 120A. Cogent Brand. 1 EA.
Additional Information:
Cogent HPS Cyano™ HPLC Columns are designed for versatile reversed-phase separations of polar and neutral compounds requiring moderate retention, rapid equilibration, and reproducible chromatographic performance. Manufactured using a monofunctional three-carbon ligand with a terminal cyano functional group bonded to high-purity 120Å silica and fully end capped, this stationary phase offers unique selectivity characteristics that are widely used as an alternative for USP L10 methods and for new method development. The HPS product line was developed to provide a high-value option for laboratories seeking performance characteristics comparable to established cyano phases used throughout pharmaceutical, environmental, and analytical laboratories.
75025-25P is packed with 5 µm HPS Cyano™ particles in a 4.6 mm ID x 250 mm analytical format. The 5 µm particle size provides reliable chromatographic efficiency with lower operating backpressure than smaller particles, while the 250 mm length delivers maximum retention, resolution, and peak capacity for complex analytical separations. This traditional analytical column format is often selected when the highest chromatographic resolving power is required.
The HPS Cyano™ stationary phase is commonly used for polar and neutral compounds analyzed using reversed-phase chromatography. Compared to non-modified silica columns, the cyano phase provides faster equiliation between runs and shorter retention times while maintaining excellent selectivity. The extended column length makes this format particularly useful for complex sample matrices, closely related compounds, and demanding analytical methods requiring maximum separation performance.
Key Benefits
HPS Cyano™ stationary phase
USP L10 equivalent chemistry
Fully end capped
Monofunctional cyano bonded phase
High-purity 120Å silica
5 µm particle size
Lower operating backpressure
Faster equilibration between runs
Shorter retention than non-modified silica
Maximum chromatographic resolution and peak capacity
Typical Applications
USP L10 methods
Reversed-phase HPLC
Polar compound analysis
Neutral compound analysis
Pharmaceutical analysis
Method development
Method validation
Routine quality control
Environmental testing
Complex sample separations
Specifications
Product Type: Analytical HPLC Column
Stationary Phase: HPS Cyano™
USP Classification: L10
Chromatography Mode: Reversed Phase
Particle Size: 5 µm
Pore Size: 120Å
Column Dimensions: 4.6 mm ID x 250 mm
Recommended Flow Rate: 1.0–2.0 mL/min
Column Hardware: Stainless Steel
Brand: Cogent
Important Notes
Suitable for reversed-phase chromatography
USP L10 equivalent chemistry
Fully end capped stationary phase
Designed for polar and neutral compounds
Provides faster equilibration than non-modified silica columns
Delivers shorter retention times than silica phases
Compatible with standard analytical HPLC systems
Frequently compared with established cyano columns from Inertsil™ and Luna™ product families
250 mm length provides maximum retention, resolution, and peak capacity
Ideal for complex separations and challenging analytical methods