HPLC Column, HPS Cyano, 5um, 4.6mm ID x 50mm Length, 120A. Cogent Brand. 1 EA.
Additional Information:
Cogent HPS Cyano™ HPLC Columns are designed for versatile reversed-phase separations of polar and neutral compounds requiring moderate retention, rapid equilibration, and reproducible chromatographic performance. Manufactured using a monofunctional three-carbon ligand with a terminal cyano functional group bonded to high-purity 120Å silica and fully end capped, this stationary phase offers unique selectivity characteristics that are widely used as an alternative for USP L10 methods and for new method development. The HPS product line was developed to provide a high-value option for laboratories seeking reliable performance for challenging separations involving polar analytes.
75025-05P is packed with 5 µm HPS Cyano™ particles in a 4.6 mm ID x 50 mm analytical format. The short 50 mm column length is optimized for rapid analysis, method development, and high-throughput workflows where reduced run times and lower solvent consumption are important. The 5 µm particle size provides reliable efficiency and lower operating backpressure compared to smaller particle columns while maintaining compatibility with conventional HPLC systems.
The HPS Cyano™ stationary phase is often selected for polar and neutral compounds analyzed using reversed-phase chromatography. Compared to non-modified silica columns, the cyano phase provides faster equilibration between runs and shorter retention times while maintaining excellent selectivity. This column is frequently used as a scouting column for preparative method development and analytical screening applications.
Key Benefits
HPS Cyano™ stationary phase
USP L10 equivalent chemistry
Fully end capped
Monofunctional cyano bonded phase
High-purity 120Å silica
5 µm particle size
Lower operating backpressure
Faster equilibration between runs
Shorter retention than non-modified silica
Ideal for rapid method development
Typical Applications
USP L10 methods
Reversed-phase HPLC
Polar compound analysis
Neutral compound analysis
Method development
Method screening
High-throughput analysis
Pharmaceutical analysis
Routine quality control
Preparative method scouting
Specifications
Product Type: Analytical HPLC Column
Stationary Phase: HPS Cyano™
USP Classification: L10
Chromatography Mode: Reversed Phase
Particle Size: 5 µm
Pore Size: 120Å
Column Dimensions: 4.6 mm ID x 50 mm
Recommended Flow Rate: 1.0–2.0 mL/min
Column Hardware: Stainless Steel
Brand: Cogent
Important Notes
Suitable for reversed-phase chromatography
USP L10 equivalent chemistry
Fully end capped stationary phase
Designed for polar and neutral compounds
Provides faster equilibration than non-modified silica columns
Delivers shorter retention times than silica phases
Compatible with standard analytical HPLC systems
Frequently used for preparative method scouting
Ideal for rapid screening and method development
50 mm length minimizes solvent usage and analysis time