HPLC Column, HPS Phenyl, 5um, 4.6mm ID x 250mm Length, 120A. Cogent Brand. 1 EA.
Additional Information:
Cogent HPS Phenyl™ HPLC Columns are designed for reversed-phase separations where aromatic selectivity and π-π interactions provide advantages over conventional alkyl-bonded phases. Manufactured using a monofunctional four-carbon ligand with an attached phenyl group bonded to high-purity 120Å silica and fully end capped for excellent peak shape and reproducibility, this stationary phase is widely used as an alternative for USP L11 methods and for developing methods involving structurally similar aromatic compounds. The HPS product line was developed to provide a high-value option for laboratories seeking performance characteristics comparable to established premium phenyl phases.
75020-25P is packed with 5 µm HPS Phenyl™ particles in a 4.6 mm ID x 250 mm analytical format. The 5 µm particle size provides reliable chromatographic efficiency with lower operating backpressure than smaller particles, while the 250 mm column length delivers maximum resolving power and peak capacity for demanding separations. This traditional analytical column format is often selected when the highest level of chromatographic resolution is required.
The HPS Phenyl™ stationary phase is especially useful for separating positional isomers, tocopherols, flavonoids, polynuclear aromatic hydrocarbons, nitro-aromatic compounds, active pharmaceutical ingredients (APIs), natural products, and related compounds. The unique aromatic selectivity frequently provides improved separation of structurally related compounds that may not be adequately resolved on traditional C18 columns, making it an excellent choice for complex reversed-phase applications and challenging method development projects.
Key Benefits
HPS Phenyl™ stationary phase
USP L11 equivalent chemistry
Fully end capped
Monofunctional phenyl bonded phase
High-purity 120Å silica
5 µm particle size
Enhanced aromatic selectivity
Excellent for positional isomer separations
Lower operating backpressure
Maximum chromatographic resolution and peak capacity
Typical Applications
USP L11 methods
Positional isomer separations
Tocopherol analysis
Flavonoid analysis
Polynuclear aromatic hydrocarbon analysis
Nitro-aromatic compound analysis
Active pharmaceutical ingredient analysis
Natural product analysis
Method development
Reversed-phase HPLC
Specifications
Product Type: Analytical HPLC Column
Stationary Phase: HPS Phenyl™
USP Classification: L11
Chromatography Mode: Reversed Phase
Particle Size: 5 µm
Pore Size: 120Å
Column Dimensions: 4.6 mm ID x 250 mm
Recommended Flow Rate: 1.0–2.0 mL/min
Column Hardware: Stainless Steel
Brand: Cogent
Important Notes
Suitable for reversed-phase chromatography
USP L11 equivalent chemistry
Fully end capped stationary phase
Provides unique aromatic and π-π interaction selectivity
Excellent for positional isomer separations
Ideal for flavonoids, tocopherols, and aromatic compounds
Compatible with standard analytical HPLC systems
250 mm length provides maximum retention, resolution, and peak capacity
Lower backpressure compared to smaller particle columns
Useful when additional selectivity beyond C18 phases is required
Excellent for complex sample matrices and difficult separations