HPLC Column, HPS Phenyl, 5um, 2.1mm ID x 100mm Length, 120A. Cogent Brand. 1 EA.
Additional Information:
Cogent HPS Phenyl™ HPLC Columns are designed for reversed-phase separations where aromatic selectivity and π-π interactions provide advantages over traditional alkyl-bonded phases. Manufactured using a monofunctional four-carbon ligand with an attached phenyl group bonded to high-purity 120Å silica and fully end capped for excellent peak shape and reproducibility, this stationary phase is widely used for challenging separations involving aromatic compounds, positional isomers, and structurally related analytes. The HPS product line was developed to provide a high-value option for laboratories seeking performance characteristics comparable to well-established premium phenyl columns used throughout pharmaceutical, environmental, and analytical laboratories.
75020-10P-2 is packed with 5 µm HPS Phenyl™ particles in a 2.1 mm ID x 100 mm analytical format. The 5 µm particle size provides reliable chromatographic efficiency with lower operating backpressure than smaller particles, while the 100 mm column length offers an excellent balance between analysis speed and chromatographic resolution. The narrow-bore format reduces solvent consumption and is particularly well suited for LC-MS workflows requiring enhanced sensitivity and efficient mobile phase utilization.
The HPS Phenyl™ stationary phase is especially useful for separating positional isomers, tocopherols, flavonoids, polynuclear aromatic hydrocarbons, nitro-aromatic compounds, active pharmaceutical ingredients (APIs), natural products, and related compounds. The aromatic selectivity provided by the phenyl ligand can improve separations that may be difficult to achieve using conventional C18 columns. This column is frequently selected for LC-MS methods where both chromatographic selectivity and sensitivity are important.
Key Benefits
HPS Phenyl™ stationary phase
Fully end capped
Monofunctional phenyl bonded phase
High-purity 120Å silica
5 µm particle size
Enhanced aromatic selectivity
Excellent for positional isomer separations
Lower operating backpressure
Reduced solvent consumption
Highly suitable for LC-MS applications
Typical Applications
LC-MS and LC-MS/MS methods
Positional isomer separations
Tocopherol analysis
Flavonoid analysis
Polynuclear aromatic hydrocarbon analysis
Nitro-aromatic compound analysis
Active pharmaceutical ingredient analysis
Natural product analysis
Method development
Reversed-phase HPLC
Specifications
Product Type: Analytical HPLC Column
Stationary Phase: HPS Phenyl™
Chromatography Mode: Reversed Phase
Particle Size: 5 µm
Pore Size: 120Å
Column Dimensions: 2.1 mm ID x 100 mm
Recommended Flow Rate: 0.2–0.3 mL/min
Column Hardware: Stainless Steel
Brand: Cogent
Important Notes
Suitable for reversed-phase chromatography
Fully end capped stationary phase
Provides unique aromatic and π-π interaction selectivity
Excellent for positional isomer separations
Ideal for flavonoids, tocopherols, and aromatic compounds
Well suited for LC-MS applications
Reduced solvent consumption compared to larger ID columns
2.1 mm ID columns require an HPLC system capable of reliable low flow rate delivery
Low-volume detector flow cells are recommended for optimal performance
100 mm length provides an excellent balance of speed and resolution