HPLC Column, HPS Phenyl, 5um, 2.1mm ID x 50mm Length, 120A. Cogent Brand. 1 EA.

Additional Information:

Cogent HPS Phenyl™ HPLC Columns are designed for reversed-phase separations where π-π interactions and aromatic selectivity provide advantages over traditional C18 phases. Manufactured using a monofunctional four-carbon ligand with an attached phenyl group bonded to high-purity 120Å silica, and fully end capped for excellent peak shape and reproducibility, this stationary phase is widely used for challenging separations involving aromatic compounds, positional isomers, and structurally related analytes. The HPS product line was developed to provide a high-value alternative for laboratories seeking performance characteristics comparable to widely used premium phenyl phases.

75020-05P-2 is packed with 5 µm HPS Phenyl™ particles in a 2.1 mm ID x 50 mm analytical format. The short 50 mm length is ideal for rapid separations, method development, and high-throughput LC-MS workflows. The 5 µm particle size provides reliable chromatographic efficiency and lower operating backpressure than smaller particles, while the narrow-bore format reduces solvent consumption and supports enhanced LC-MS sensitivity when paired with appropriate instrumentation.

The HPS Phenyl™ stationary phase is particularly useful for separating positional isomers, tocopherols, flavonoids, polynuclear aromatic hydrocarbons, nitro-aromatic compounds, active pharmaceutical ingredients (APIs), natural products, and related compounds. The unique aromatic selectivity can provide separation mechanisms not achievable with conventional alkyl-bonded reversed-phase columns, making it a valuable tool for difficult method development challenges.

Key Benefits

  • HPS Phenyl™ stationary phase

  • Fully end capped

  • Monofunctional phenyl bonded phase

  • High-purity 120Å silica

  • 5 µm particle size

  • Enhanced aromatic selectivity

  • Excellent for positional isomer separations

  • Lower operating backpressure

  • Reduced solvent consumption

  • Highly suitable for LC-MS applications

Typical Applications

  • LC-MS and LC-MS/MS methods

  • Positional isomer separations

  • Tocopherol analysis

  • Flavonoid analysis

  • Polynuclear aromatic hydrocarbon analysis

  • Nitro-aromatic compound analysis

  • Active pharmaceutical ingredient analysis

  • Natural product analysis

  • Method development

  • Reversed-phase HPLC

Specifications

  • Product Type: Analytical HPLC Column

  • Stationary Phase: HPS Phenyl™

  • Chromatography Mode: Reversed Phase

  • Particle Size: 5 µm

  • Pore Size: 120Å

  • Column Dimensions: 2.1 mm ID x 50 mm

  • Recommended Flow Rate: 0.2–0.3 mL/min

  • Column Hardware: Stainless Steel

  • Brand: Cogent

Important Notes

  • Suitable for reversed-phase chromatography

  • Fully end capped stationary phase

  • Provides unique aromatic and π-π interaction selectivity

  • Excellent for positional isomer separations

  • Ideal for flavonoids, tocopherols, and aromatic compounds

  • Highly suitable for LC-MS applications

  • Reduced solvent consumption compared to larger ID columns

  • 2.1 mm ID columns require an HPLC system capable of reliable low flow rate delivery

  • Low-volume detector flow cells are recommended for optimal performance

  • 50 mm length minimizes analysis time and solvent usage


 

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