Prep HPLC Column, HPS C18, 5um, 120A. 21.2mm ID x 50mm Length. Cogent Brand. 1 EA.
Additional Info:
The 75018‑P50 Cogent HPS C18™ Preparative Column is designed for fast, high‑throughput purification and scalable reversed‑phase workflows, delivering strong retention, clean peak shape, and reliable selectivity.
Manufactured with high‑purity silica, monofunctional C18 bonding, and full double end‑capping, this stationary phase minimizes secondary interactions and ensures consistent chromatographic behavior during scale‑up from analytical and semi‑prep methods.
This column is especially effective for purification of hydrophobic and neutral compounds, including long‑chain fatty acids, where speed and throughput are key drivers.
50 mm Length – Fast Prep Purification & Throughput
The 50 mm length is optimized for rapid purification cycles, making it ideal for high‑throughput environments and early‑stage preparative work.
Fast run times and quick turnaround
Reduced solvent consumption
Efficient for preparative screening and bulk processing
✅ Use when speed and throughput are prioritized over maximum resolution
Flow Rate & System Requirements (21.2 mm ID, 5 µm)
⚠️ Requires a preparative HPLC system capable of high flow rates and large injection volumes
Typical flow rate range: ~15–40 mL/min
High sample loading capacity required
Detector must support preparative flow cell volumes
System must provide stable, high‑flow operation
✅ Sample preparation requirement: use appropriate filtration (0.2 µm or 0.45 µm) to prevent clogging and protect column lifetime
Why Choose HPS C18 for Preparative Work
High‑Throughput Purification
Short length reduces cycle time
Ideal for repetitive purification runs
Scalable Method Transfer
Maintains selectivity from 4.6 mm → 10 mm → 21.2 mm
Enables seamless transition from analytical to prep
High‑Purity Silica Performance
Reduces secondary interactions
Improves reproducibility and fraction consistency
Cogent HPS C18™ Advantages
Fully End‑Capped Surface
Minimizes silanol activity
Improves peak shape for difficult analytes
Monofunctional Bonding
Predictable and stable retention behavior
Consistent selectivity across methods
Optimized for Preparative Use
Lower backpressure vs smaller particles
Durable under repeated high‑load injections
Typical Applications
Preparative purification
High‑throughput compound isolation
Method scale‑up from analytical and semi‑prep
Hydrophobic and neutral compound purification
Process development workflows
Important Usage Notes
Requires preparative HPLC system (21.2 mm ID compatibility)
Not suitable for analytical systems
👉 Made‑to‑Order Columns & Pricing Information
This is a custom, made‑to‑order column.
Columns are manufactured specifically to order
Orders cannot be canceled once placed
Custom columns are non‑returnable