HPLC Column, HPS C18, 5um, 2.1mm ID x 50mm Length, 120A. Cogent Brand. 1 EA.
Additional Information:
Cogent HPS C18™ HPLC Columns are designed for high-purity, reproducible reversed-phase separations using monofunctional C18 bonding on proprietary high-purity silica with full double end capping. This stationary phase provides excellent peak shape, consistent selectivity, and low background interference, making it ideal for USP L1 methods and new analytical method development. The HPS product line was developed to provide a high-value alternative for laboratories seeking performance characteristics similar to many well-established premium C18 columns used in pharmaceutical, environmental, food, and analytical testing laboratories.
75018-05P-2 is packed with 5 µm HPS C18™ particles in a 2.1 mm ID x 50 mm analytical format with a 120Å pore size. The short 50 mm length is optimized for rapid separations, method development, and high-throughput LC-MS workflows where minimizing solvent consumption and analysis time is critical. The narrow-bore 2.1 mm format reduces solvent usage and can enhance LC-MS sensitivity when operated on systems capable of delivering precise low flow rates.
The HPS C18™ stationary phase is well suited for hydrophobic and neutral analytes requiring stronger retention than C8 phases. The 120Å pore size provides excellent versatility across a wide range of compounds, including moderately larger and more complex molecules. This column is frequently selected for LC-MS/MS workflows, pharmaceutical analysis, USP L1 methods, trace-level detection, and general-purpose reversed-phase chromatography applications.
Key Benefits
HPS C18™ stationary phase
USP L1 equivalent chemistry
Monofunctional C18 bonding
Fully double end capped
Proprietary high-purity silica
120Å pore size
5 µm particle size
Low-flow LC-MS compatible format
Lower backpressure than smaller particles
Ideal for fast analysis and high-sensitivity detection
Typical Applications
LC-MS and LC-MS/MS workflows
USP L1 analytical methods
Pharmaceutical QC
Method development
High-throughput screening
Trace-level analysis
Hydrophobic compound separations
Neutral analyte analysis
Long-chain fatty acid analysis
General reversed-phase chromatography
Specifications
Product Type: Analytical HPLC Column
Stationary Phase: HPS C18™
USP Classification: L1
Chromatography Mode: Reversed Phase
Particle Size: 5 µm
Pore Size: 120Å
Column Dimensions: 2.1 mm ID x 50 mm
Recommended Flow Rate: 0.2–0.3 mL/min
Column Hardware: Stainless Steel
Brand: Cogent
Important Notes
Suitable for low-flow LC-MS and LC-MS/MS applications
Fully double end capped stationary phase
Provides greater retention than C8 phases
Excellent peak shape and analytical reproducibility
Ideal for rapid screening and method development workflows
Compatible with USP L1 methods
High-purity silica minimizes unwanted secondary interactions
2.1 mm ID columns require an HPLC system capable of reliable low flow rate delivery
Low-volume detector flow cells are recommended for optimal performance
Sample preparation using 0.2 µm syringe filters is recommended
50 mm length minimizes solvent consumption and analysis time