HPLC Column, HPS C18, 5um, 4.6mm ID x 50mm Length, 120A. Cogent Brand. 1 EA.

Additional Information:

Cogent HPS C18™ HPLC Columns are designed for high-purity, reproducible reversed-phase separations using monofunctional C18 bonding on proprietary high-purity silica with full double end capping. This stationary phase provides excellent peak shape, consistent selectivity, and reliable retention, making it ideal for USP L1 methods and new analytical method development. The HPS product line was developed to provide a high-value alternative for laboratories seeking performance characteristics similar to many well-established premium C18 columns used in pharmaceutical, environmental, food, and analytical testing laboratories.

75018-05P is packed with 5 µm HPS C18™ particles in a 4.6 mm ID x 50 mm analytical format with a 120Å pore size. The short 50 mm length is optimized for rapid separations, method development, and high-throughput screening applications where minimizing solvent consumption and analysis time is important. The 5 µm particle size provides reliable efficiency, lower operating backpressure, and excellent compatibility with conventional HPLC systems.

The HPS C18™ stationary phase is well suited for hydrophobic and neutral analytes requiring stronger retention than C8 phases. The 120Å pore size provides excellent versatility across a wide range of compounds, including slightly larger and more complex molecules. This column is frequently selected for routine quality control, pharmaceutical analysis, method development, and general-purpose reversed-phase chromatography workflows.

Key Benefits

  • HPS C18™ stationary phase

  • USP L1 equivalent chemistry

  • Monofunctional C18 bonding

  • Fully double end capped

  • Proprietary high-purity silica

  • 120Å pore size

  • 5 µm particle size

  • Lower backpressure than smaller particles

  • Stronger retention than C8 phases

  • Ideal for rapid analysis and method development

Typical Applications

  • USP L1 analytical methods

  • Pharmaceutical QC

  • Method development

  • Method validation

  • High-throughput screening

  • Routine HPLC analysis

  • Hydrophobic compound separations

  • Neutral analyte analysis

  • Long-chain fatty acid analysis

  • General reversed-phase chromatography

Specifications

  • Product Type: Analytical HPLC Column

  • Stationary Phase: HPS C18™

  • USP Classification: L1

  • Chromatography Mode: Reversed Phase

  • Particle Size: 5 µm

  • Pore Size: 120Å

  • Column Dimensions: 4.6 mm ID x 50 mm

  • Recommended Flow Rate: 0.8–1.5 mL/min

  • Column Hardware: Stainless Steel

  • Brand: Cogent

Important Notes

  • Suitable for standard analytical HPLC systems

  • Fully double end capped stationary phase

  • Provides greater retention than C8 phases

  • Excellent peak shape and reproducibility

  • Ideal for rapid screening workflows

  • Optimized for method development and routine analysis

  • Compatible with USP L1 methods

  • High-purity silica minimizes unwanted secondary interactions

  • Sample preparation using 0.2 µm syringe filters is recommended

  • 50 mm length minimizes solvent consumption and analysis time


 

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