Catalog Number - 75008-7.5P

Cogent HPS C8™ HPLC Columns are designed for reversed-phase separations requiring moderate hydrophobic retention, excellent peak shape, and reproducible performance. Manufactured using a unique 120Å silica support with monofunctional octyl (C8) bonding and full double end capping, this stationary phase is widely used as an alternative for USP L7 methods and for new method development. The HPS product line was developed to provide a high-value option for laboratories seeking performance characteristics similar to widely established octyl phases used throughout pharmaceutical, environmental, food, and analytical laboratories.

75008-7.5P is packed with 5 µm HPS C8™ particles in a 4.6 mm ID x 75 mm analytical format. This intermediate-length column provides greater resolving power than a 50 mm column while maintaining shorter run times than traditional 150 mm and 250 mm formats. The 5 µm particle size offers reliable chromatographic efficiency with lower operating backpressure than smaller particles, making it suitable for virtually all conventional HPLC systems.

The HPS C8™ stationary phase is well suited for hydrophobic and neutral compounds analyzed under reversed-phase conditions. Compared to C18 columns, the octyl phase generally provides shorter retention, making it useful for compounds that are overly retained on more hydrophobic stationary phases. This column is particularly effective for long-chain fatty acids and is an excellent choice when a balance of speed, efficiency, and resolution is required.

Key Benefits

• HPS C8™ stationary phase

• USP L7 equivalent chemistry

• Monofunctional octyl (C8) bonding

• Fully double end capped

• Unique 120Å silica support

• 5 µm particle size

• Lower operating backpressure

• Shorter retention than C18 phases

• Excellent for long-chain fatty acids

• Balanced speed and resolution

Typical Applications

• Reversed-phase HPLC

• USP L7 methods

• Fatty acid analysis

• Hydrophobic compound separations

• Neutral compound analysis

• Pharmaceutical analysis

• Food testing

• Environmental analysis

• Method development

• Routine quality control

Specifications

• Product Type: Analytical HPLC Column

• Stationary Phase: HPS C8™ Octyl

• USP Classification: L7

• Chromatography Mode: Reversed Phase

• Particle Size: 5 µm

• Pore Size: 120Å

• Column Dimensions: 4.6 mm ID x 75 mm

• Recommended Flow Rate: 1.0–2.0 mL/min

• Column Hardware: Stainless Steel

• Brand: Cogent

Important Notes

• Suitable for reversed-phase chromatography

• Fully double end capped stationary phase

• Provides shorter retention than C18 columns

• Excellent for long-chain fatty acid analysis

• Well suited for hydrophobic and neutral compounds

• Compatible with standard analytical HPLC systems

• Provides greater resolution than a 50 mm column with shorter run times than longer formats

• Ideal for routine analytical methods and method development

• USP L7 equivalent chemistry

• 75 mm length offers an excellent balance of throughput and chromatographic performance

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