HPLC Column, HPS C8 Octyl, 5um, 4.6mm ID x 250mm Length, 120A. Cogent Brand. 1 EA.
Additional Information:
Cogent HPS C8™ HPLC Columns are designed for reversed-phase separations requiring moderate hydrophobic retention, excellent peak shape, and reproducible performance. Manufactured using a unique 120Å silica support with monofunctional octyl (C8) bonding and full double end capping, this stationary phase is widely used as an alternative for USP L7 methods and for new method development. The HPS product line was developed to provide a high-value option for laboratories seeking performance characteristics similar to widely established octyl phases used throughout pharmaceutical, environmental, food, and analytical laboratories.
75008-25P is packed with 5 µm HPS C8™ particles in a 4.6 mm ID x 250 mm analytical format. The 5 µm particle size provides reliable chromatographic efficiency with lower operating backpressure than smaller particles, while the 250 mm column length delivers maximum resolving power and peak capacity. This format is particularly useful when separating complex sample matrices or closely related compounds that require enhanced retention and resolution.
The HPS C8™ stationary phase is well suited for hydrophobic and neutral compounds analyzed under reversed-phase conditions. Compared to C18 columns, the octyl phase generally provides shorter retention, making it useful for compounds that are excessively retained on more hydrophobic stationary phases. This column is particularly effective for long-chain fatty acids and remains a popular choice for many established analytical methods and legacy USP L7 applications.
Key Benefits
HPS C8™ stationary phase
USP L7 equivalent chemistry
Monofunctional octyl (C8) bonding
Fully double end capped
Unique 120Å silica support
5 µm particle size
Lower operating backpressure
Shorter retention than C18 phases
Excellent for long-chain fatty acids
Maximum chromatographic resolution
Typical Applications
Reversed-phase HPLC
USP L7 methods
Fatty acid analysis
Hydrophobic compound separations
Neutral compound analysis
Pharmaceutical analysis
Food testing
Environmental analysis
Method validation
Routine quality control
Specifications
Product Type: Analytical HPLC Column
Stationary Phase: HPS C8™ Octyl
USP Classification: L7
Chromatography Mode: Reversed Phase
Particle Size: 5 µm
Pore Size: 120Å
Column Dimensions: 4.6 mm ID x 250 mm
Recommended Flow Rate: 1.0–2.0 mL/min
Column Hardware: Stainless Steel
Brand: Cogent
Important Notes
Suitable for reversed-phase chromatography
Fully double end capped stationary phase
Provides shorter retention than C18 columns
Excellent for long-chain fatty acid analysis
Well suited for hydrophobic and neutral compounds
Compatible with standard analytical HPLC systems
Traditional column format used in many established and legacy methods
250 mm length provides maximum retention, resolution, and peak capacity
Ideal for complex sample separations
USP L7 equivalent chemistry