HPLC Column, HPS C8 Octyl, 5um, 2.1mm ID x 50mm Length, 120A. Cogent Brand. 1 EA.
Additional Information:
Cogent HPS C8™ HPLC Columns are designed for reversed-phase separations requiring moderate hydrophobic retention, excellent peak shape, and reproducible performance. Built on a unique 120Å silica support with monofunctional octyl (C8) bonding and full double end capping, this stationary phase is widely used as an alternative for USP L7 methods and for new method development. The HPS product line was developed to provide a high-value option for laboratories seeking performance characteristics associated with well-established octyl phases used throughout pharmaceutical, environmental, and analytical laboratories.
75008-05P-2 is packed with 5 µm HPS C8™ particles in a 2.1 mm ID x 50 mm analytical format. The 5 µm particle size provides reliable efficiency with lower operating backpressure than smaller particles, while the short 50 mm length enables rapid analyses and high-throughput screening. This narrow-bore format reduces solvent consumption and is particularly beneficial when sample mass is limited or LC-MS compatibility is desired.
The HPS C8™ stationary phase is well suited for hydrophobic and neutral compounds analyzed under reversed-phase conditions. Compared to C18 columns, the octyl phase generally provides shorter retention, making it useful for compounds that are excessively retained on more hydrophobic stationary phases. This column is especially effective for long-chain fatty acids and is a popular choice for LC-MS methods, provided the HPLC system can accurately deliver and monitor the lower flow rates required by 2.1 mm ID columns.
Key Benefits
HPS C8™ stationary phase
USP L7 equivalent chemistry
Monofunctional octyl (C8) bonding
Fully double end capped
Unique 120Å silica support
5 µm particle size
Lower solvent consumption
Shorter retention than C18 phases
Excellent for long-chain fatty acids
Popular format for LC-MS applications
Typical Applications
Reversed-phase HPLC
LC-MS methods
USP L7 methods
Fatty acid analysis
Hydrophobic compound separations
Neutral compound analysis
Method development
High-throughput analysis
Pharmaceutical analysis
Screening methods
Specifications
Product Type: Analytical HPLC Column
Stationary Phase: HPS C8™ Octyl
USP Classification: L7
Chromatography Mode: Reversed Phase
Particle Size: 5 µm
Pore Size: 120Å
Column Dimensions: 2.1 mm ID x 50 mm
Recommended Flow Rate: 0.2–0.3 mL/min
Column Hardware: Stainless Steel
Brand: Cogent
Important Notes
Suitable for reversed-phase chromatography
Fully double end capped stationary phase
Provides shorter retention than C18 columns
Excellent for long-chain fatty acid analysis
Well suited for hydrophobic and neutral compounds
Ideal for LC-MS applications
Reduces solvent consumption compared to larger ID columns
2.1 mm ID columns require an HPLC system capable of delivering reliable low flow rates
Low-volume detector flow cells are recommended for optimal performance
50 mm length minimizes analysis time
USP L7 equivalent chemistry