HPLC Column, NP Amino, 5um, 4.6mm ID x 250mm Length, 100A. Cogent Brand. 1 EA.

Additional Information:

Cogent NP Amino™ HPLC Columns are designed for Normal Phase and HILIC separations of highly polar compounds. Manufactured using ultra-high purity silica bonded with a three-carbon propyl linker and terminal amino functionality, this stationary phase provides the selectivity needed for retention and separation of compounds that can be difficult to retain using traditional reversed-phase chromatography. NP Amino™ is an excellent alternative for USP L8 methods, including Grace Alltima™ Amino columns, as well as for new method development involving polar analytes.

68540-25P is packed with 5 µm NP Amino™ particles in a 4.6 mm ID x 250 mm format with a 100Å pore size. The 5 µm particle size provides reliable performance with moderate backpressure while maintaining excellent reproducibility. The extended 250 mm column length provides maximum resolving power and increased peak capacity, making it ideal for complex separations, method optimization, and analytical methods requiring enhanced retention and resolution.

The amino stationary phase is not end capped and is particularly useful for sugars, carbohydrates, organic acids, and other highly polar compounds containing hydroxyl or carboxylic acid functionalities. This column can be used in Normal Phase and HILIC chromatographic modes and is packed and shipped in normal-phase solvents. Recognized for its robustness, versatility, and reproducibility, this column has become a trusted choice for both established USP methods and innovative method development projects.

Key Benefits

  • NP Amino™ stationary phase

  • USP L8 equivalent chemistry

  • Alternative to Grace Alltima™ Amino columns

  • Ultra-high purity silica support

  • Three-carbon propyl linker with terminal amino group

  • Not end capped

  • 100Å pore size

  • Suitable for Normal Phase chromatography

  • Suitable for HILIC applications

  • Maximum resolution for demanding separations

Typical Applications

  • Normal Phase HPLC

  • HILIC chromatography

  • USP L8 methods

  • Sugar analysis

  • Carbohydrate separations

  • Organic acid analysis

  • Polar compound separations

  • Food and beverage testing

  • Pharmaceutical analysis

  • Method development

Specifications

  • Product Type: HPLC Column

  • Stationary Phase: NP Amino™

  • Chromatography Mode: Normal Phase / HILIC

  • USP Classification: L8

  • Particle Size: 5 µm

  • Pore Size: 100Å

  • Column Dimensions: 4.6 mm ID x 250 mm

  • Recommended Flow Rate: 1.0–2.0 mL/min

  • Column Hardware: Stainless Steel

  • Brand: Cogent

Important Notes

  • Suitable for Normal Phase chromatography

  • Suitable for HILIC applications

  • USP L8 equivalent chemistry

  • Alternative to Grace Alltima™ Amino columns

  • Not end capped

  • Designed for separation of highly polar compounds

  • Frequently used for sugars and compounds containing carboxylic acid groups

  • Packed and shipped in normal-phase solvents

  • 250 mm length provides maximum retention and resolution

  • Provides an alternative retention mechanism to reversed-phase chromatography

  • Popular for USP methods and new method development


 

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