HPLC Column, RP Phenyl Hexyl, 5um, 4.6mm ID x 50mm Length, 100A. Cogent Brand. 1 EA.
Additional Information:
Cogent RP Phenyl Hexyl™ HPLC Columns are designed for reversed-phase separations where enhanced aromatic selectivity and strong π-π interactions are desired. Manufactured using ultra-high purity silica bonded with a six-carbon linker and terminal Phenyl group, this stationary phase is fully double end-capped to minimize secondary interactions and provide highly reproducible chromatographic performance. RP Phenyl Hexyl™ is an excellent alternative for certain USP L11 methods that specify or benefit from Phenyl Hexyl selectivity.
68539-05P is packed with 5 µm RP Phenyl Hexyl™ particles in a 4.6 mm ID x 50 mm format with a 100Å pore size. The 5 µm particle size provides lower operating backpressure than smaller particles while maintaining excellent efficiency and reproducibility. The short 50 mm column length is ideal for rapid analyses, method development, and high-throughput laboratories seeking reduced run times and solvent consumption.
The six-carbon linker positions the Phenyl group farther from the silica surface, increasing π-π interactions while reducing the influence of residual silanol activity. This enhanced selectivity can improve retention and separation of many aromatic and moderately polar analytes including positional isomers, tocopherols, flavonoids, polynuclear aromatic hydrocarbons, nitro-aromatic compounds, active pharmaceutical ingredients (APIs), natural products, and related compounds. For optimized π-π interactions, methanol is often preferred over acetonitrile as the organic modifier.
Key Benefits
RP Phenyl Hexyl™ stationary phase
USP L11 equivalent chemistry
Ultra-high purity silica support
Fully double end-capped
Six-carbon linker with terminal Phenyl group
100Å pore size
Suitable for reversed-phase chromatography
Enhanced π-π interactions
Alternative selectivity to conventional Phenyl phases
Ideal for rapid analytical methods
Typical Applications
Reversed-phase HPLC
USP L11 methods
Aromatic compound separations
Positional isomer separations
Tocopherol analysis
Flavonoid analysis
Polynuclear aromatic hydrocarbon analysis
Nitro-aromatic compound separations
Active pharmaceutical ingredient (API) analysis
Natural product analysis
Specifications
Product Type: HPLC Column
Stationary Phase: RP Phenyl Hexyl™
Chromatography Mode: Reversed Phase
USP Classification: L11
Particle Size: 5 µm
Pore Size: 100Å
Column Dimensions: 4.6 mm ID x 50 mm
Recommended Flow Rate: 1.0–2.0 mL/min
Column Hardware: Stainless Steel
Brand: Cogent
Important Notes
Suitable for reversed-phase chromatography
USP L11 equivalent chemistry
Fully double end-capped
Enhanced π-π interactions improve aromatic selectivity
Six-carbon linker increases distance from the silica surface
Excellent for aromatic, polar, and structurally related compounds
Short 50 mm length helps reduce run times and solvent consumption
Methanol is often preferred over acetonitrile when maximizing π-π interactions
Ideal for rapid screening and method development