Catalog Number - 68534-PG2

Cogent RP Cyano™ Guard Column Cartridges are designed to protect analytical HPLC columns from particulates, strongly retained compounds, and other contaminants that can reduce column performance and shorten column life. Packed with the same stationary phase as the analytical column, these guard cartridges help maintain chromatographic performance while reducing the frequency and cost of analytical column replacement.

68534-PG2 is packed with 5 µm RP Cyano™ stationary phase featuring a 100Å pore size. Manufactured using ultra-high purity silica bonded with a three-carbon ligand and terminal Cyano functionality, this stationary phase is not end capped and provides the distinctive selectivity associated with USP L10 chemistry. The cartridges are packed and shipped in reversed-phase solvents and housed in stainless steel tubing with stainless steel frits secured within durable PEEK frit caps.

The 4.0 mm ID x 10 mm format is designed to protect 3.0 mm, 4.0 mm, and 4.6 mm ID RP Cyano™ analytical HPLC columns from particulate contamination and strongly retained sample components. Routine guard cartridge replacement helps maintain column efficiency, reduce downtime, and extend analytical column service life.

Key Benefits

• RP Cyano™ stationary phase

• USP L10 equivalent chemistry

• Ultra-high purity silica support

• Not end capped

• Three-carbon linker with terminal Cyano group

• 100Å pore size

• Suitable for reversed-phase chromatography

• Protects analytical columns from contamination

• Extends analytical column life

• Stainless steel cartridge construction with PEEK frit caps

Typical Applications

• Analytical HPLC

• Column protection

• Polar compound analysis

• Neutral compound separations

• Pharmaceutical analysis

• Method development

• Quality control testing

• Chemical analysis

• Alternative selectivity methods

• Routine guard cartridge replacement

Specifications

• Product Type: Guard Column Cartridges

• Stationary Phase: RP Cyano™

• Chromatography Mode: Reversed Phase

• USP Classification: L10

• Particle Size: 5 µm

• Pore Size: 100Å

• Cartridge Dimensions: 4.0 mm ID x 10 mm

• Construction: Stainless Steel Cartridge

• Frit Material: Stainless Steel with PEEK Frit Caps

• Quantity: 5/PK

• Brand: Cogent

Guard Column Requirements

• A 83000-GH Guard Column Holder is required for use with these guard column cartridges.

• Designed for use with compatible Cogent RP Cyano™ 3.0 mm, 4.0 mm, and 4.6 mm ID analytical HPLC columns.

Important Notes

• Suitable for reversed-phase chromatography

• USP L10 equivalent chemistry

• Not end capped

• Designed to protect RP Cyano™ analytical columns from particulates and strongly retained contaminants

• Helps extend analytical column life and maintain chromatographic performance

• Compatible with 3.0 mm, 4.0 mm, and 4.6 mm ID analytical columns

• Requires a compatible Guard Column Holder

• Packed and shipped in reversed-phase solvents

• See Cogent NP Cyano Columns Packed in Normal-Phase Solvents for normal-phase chromatography applications

• Intended for routine replacement as part of preventive maintenance