Guard Column Cartridges, RP Cyano Wide Pore, 5um, 300A. 2.1mm ID x 10mm Length. Cogent Brand. 5/PK.

Additional Information:

Cogent RP Cyano™ Wide Pore Guard Column Cartridges are designed to protect analytical HPLC columns from particulates, strongly retained compounds, and other contaminants that can reduce column performance and shorten column life. Packed with the same stationary phase as the analytical column, these guard cartridges help preserve chromatographic performance while reducing the frequency and cost of analytical column replacement.

68534-PG1-3 is packed with 5 µm RP Cyano™ Wide Pore stationary phase featuring a 300Å pore size. Manufactured using ultra-high purity silica bonded with a three-carbon ligand and terminal Cyano functionality, this stationary phase is not end capped and provides the unique selectivity associated with USP L10 chemistry. The wide pore structure improves accessibility for larger molecules while maintaining the distinct separation characteristics of RP Cyano™ chemistry. The cartridges are packed and shipped in reversed-phase solvents and housed in stainless steel tubing with stainless steel frits secured within durable PEEK frit caps.

The 2.1 mm ID x 10 mm format is specifically designed to protect 2.1 mm ID RP Cyano™ Wide Pore analytical HPLC columns from particulate contamination and strongly retained sample components. Routine guard cartridge replacement helps maintain column efficiency, reduce downtime, and extend analytical column service life.

Key Benefits

  • RP Cyano™ Wide Pore stationary phase

  • USP L10 equivalent chemistry

  • Ultra-high purity silica support

  • Not end capped

  • Three-carbon linker with terminal Cyano group

  • 300Å pore size

  • Suitable for reversed-phase chromatography

  • Protects analytical columns from contamination

  • Extends analytical column life

  • Enhanced accessibility for larger molecules

Typical Applications

  • Analytical HPLC

  • LC-MS methods

  • Column protection

  • Protein analysis

  • Peptide separations

  • Enzyme analysis

  • Natural product analysis

  • Polar compound separations

  • Alternative selectivity methods

  • Routine guard cartridge replacement

Specifications

  • Product Type: Guard Column Cartridges

  • Stationary Phase: RP Cyano™ Wide Pore

  • Chromatography Mode: Reversed Phase

  • USP Classification: L10

  • Particle Size: 5 µm

  • Pore Size: 300Å

  • Cartridge Dimensions: 2.1 mm ID x 10 mm

  • Construction: Stainless Steel Cartridge

  • Frit Material: Stainless Steel with PEEK Frit Caps

  • Quantity: 5/PK

  • Brand: Cogent

Guard Column Requirements

Important Notes

  • Suitable for reversed-phase chromatography

  • USP L10 equivalent chemistry

  • Not end capped

  • Wide pore structure improves accessibility for proteins, peptides, and other large molecules

  • Designed to protect RP Cyano™ Wide Pore analytical columns from particulates and strongly retained contaminants

  • Helps extend analytical column life and maintain chromatographic performance

  • Designed specifically for 2.1 mm ID analytical columns

  • Requires a compatible Guard Column Holder

  • Packed and shipped in reversed-phase solvents

  • See Cogent NP Cyano Columns Packed in Normal-Phase Solvents for normal-phase chromatography applications

  • Intended for routine replacement as part of preventive maintenance


 

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