HPLC Column, RP Cyano, 5um, 4.6mm ID x 250mm Length, 100A. Cogent Brand. 1 EA.
Additional Information:
Cogent RP Cyano™ HPLC Columns are designed for reversed-phase separations of polar and neutral compounds where alternative selectivity to traditional alkyl-bonded phases is desired. Manufactured using ultra-high purity silica bonded with a three-carbon ligand and terminal Cyano functionality, this stationary phase provides unique chromatographic characteristics that make it an excellent choice for USP L10 methods. RP Cyano™ is often selected when shorter retention, rapid equilibration, and different selectivity than C18 columns are required.
68534-25P is packed with 5 µm RP Cyano™ particles in a 4.6 mm ID x 250 mm format with a 100Å pore size. The 5 µm particle size provides lower operating backpressure than smaller particles while maintaining excellent efficiency and reproducibility. The extended 250 mm column length provides maximum resolving power and improved peak capacity, making it ideal for complex separations, method development, and analytical methods requiring enhanced resolution.
The RP Cyano™ stationary phase is not end capped and is frequently used for analysis of polar and neutral compounds in reversed-phase HPLC. Compared to non-modified silica columns, it provides shorter retention times and faster equilibration between runs. Packed and shipped in reversed-phase solvents. See Cogent NP Cyano Columns Packed in Normal-Phase Solvents for applications requiring normal-phase chromatography. This is one of the most popular RP Cyano™ column configurations.
Key Benefits
RP Cyano™ stationary phase
USP L10 equivalent chemistry
Ultra-high purity silica support
Three-carbon linker with terminal Cyano group
Not end capped
100Å pore size
Suitable for reversed-phase chromatography
Alternative selectivity to C18 and C8 columns
Faster equilibration between runs
Maximum resolution for complex separations
Typical Applications
Reversed-phase HPLC
USP L10 methods
Polar compound separations
Neutral compound separations
Pharmaceutical analysis
Method development
Quality control testing
Chemical analysis
Complex sample separations
Alternative selectivity screening
Specifications
Product Type: HPLC Column
Stationary Phase: RP Cyano™
Chromatography Mode: Reversed Phase
USP Classification: L10
Particle Size: 5 µm
Pore Size: 100Å
Column Dimensions: 4.6 mm ID x 250 mm
Recommended Flow Rate: 1.0–2.0 mL/min
Column Hardware: Stainless Steel
Brand: Cogent
Important Notes
Suitable for reversed-phase chromatography
USP L10 equivalent chemistry
Not end capped
Provides alternative selectivity compared to C18 and C8 columns
Often used for polar and neutral compounds
Faster equilibration than non-modified silica columns
250 mm length provides maximum resolution and peak capacity
Packed and shipped in reversed-phase solvents
One of the most popular RP Cyano™ column formats